Results 181 to 190 of about 6,095,243 (366)

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

open access: yesFEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti   +8 more
wiley   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

open access: yesFEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko   +2 more
wiley   +1 more source

Validity of two subjective skin tone scales and its implications on healthcare model fairness. [PDF]

open access: yesNPJ Digit Med
Cu CW   +15 more
europepmc   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

open access: yesFEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel   +9 more
wiley   +1 more source

Repeat selective dorsal rhizotomy for residual spasticity: illustrative case. [PDF]

open access: yesJ Neurosurg Case Lessons
Ledbetter E   +4 more
europepmc   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

open access: yesFEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Patriotische und chauvinistische Töne in der politischen Lyrik der deutschen und kroatischen Literatur des 19. Jahrhunderts

open access: yesZagreber germanistische Beitraege : Jahrbuch fuer Literatur- und Sprachwissenschaft, 2002
Der Vergleich patriotischer und chauvinistischer Töne in der Lyrik der Kroaten - als einer 'kleineren' Nation mit jahrhundertealter Frustration nationalstaatlicher Bestrebungen - und der Deutschen - als einer 'größeren' europäischen Nation mit Weltmachtappetiten - führt zu aufschlussreichen Ergebnissen, die von interessanten Ähnlichkeiten und komplexen
openaire   +1 more source

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