Results 51 to 60 of about 787,483 (324)

The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation

open access: yesFEBS Letters, EarlyView.
Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa   +8 more
wiley   +1 more source

Reproducibility (test-retest) of vestibular evoked myogenic potential

open access: yesBrazilian Journal of Otorhinolaryngology, 2015
INTRODUCTION: There is still no consensus in the literature as to the best acoustic stimulus for capturing vestibular evoked myogenic potential (VEMP). Low-frequency tone bursts are generally more effective than high-frequency, but recent studies still ...
Aline Cabral de Oliveira   +2 more
doaj   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Muscle Tone Assessment by Machine Learning Using Surface Electromyography

open access: yesSensors
Muscle tone is defined as the resistance to passive stretch, but this definition is often criticized for its ambiguity since some suggest it is related to a state of preparation for movement.
Andressa Rastrelo Rezende   +4 more
doaj   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Methods used to investigate tone of pelvic floor muscles in pelvic health conditions: A systematic review

open access: yesContinence, 2023
Aim:: This study aimed to systematically review which tools and outcome measures have been used to assess increased tone of PFM in pelvic health conditions. Methods:: Databases were searched for papers that studied increased PFM tone in any pelvic health
Rachel Worman   +3 more
doaj  

THE ROLE OF DICTION IN SHAPING TONE IN LITERATURE

open access: yes
This article has shown that diction by the author is a lynchpin in setting up the tone for any work an author creates. It starts by defining what exactly diction is: its various constituents being vocabulary, syntax, and formality-and it has highlighted how these choices influence the emotional response a reader will have with the text.
Ma'ripov Jalolxon Kamoliddin o'g'li   +1 more
openaire   +2 more sources

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

open access: yesFEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan   +10 more
wiley   +1 more source

The influence of directors’ and officers’ liability insurance on management tone manipulation – evidence from China

open access: yesChina Accounting and Finance Review
This paper explores the association between directors’ and officers’ liability insurance (D&O insurance) and management tone manipulation. This study uses data from A-share listed non-financial companies from 2009 to 2021 as its sample for empirical ...
Wei Xiong   +3 more
doaj   +1 more source

Inward Rectifier Potassium Channels: Membrane Lipid-Dependent Mechanosensitive Gates in Brain Vascular Cells

open access: yesFrontiers in Cardiovascular Medicine, 2022
Cerebral arteries contain two primary and interacting cell types, smooth muscle (SMCs) and endothelial cells (ECs), which are each capable of sensing particular hemodynamic forces to set basal tone and brain perfusion.
Maria Sancho   +3 more
doaj   +1 more source

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