Results 71 to 80 of about 807,723 (325)

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

An experimental study of airfoil instability tonal noise with trailing edge serrations [PDF]

open access: yes, 2013
This paper presents an experimental study of the effect of trailing edge serrations on airfoil instability noise. Detailed aeroacoustic measurements are presented of the noise radiated by an NACA-0012 airfoil with trailing edge serrations in a low to ...
Arbey   +27 more
core   +1 more source

Effects of Low- and High-Frequency Side Bands of Notched Noise on Masking and Auditory Filter Shape at Very High Frequencies

open access: yesArchives of Acoustics, 2015
This paper is concerned with the determination of the auditory filter shape using the notched noise method with noise bands symmetrically located above and below a probe frequency of 10 kHz.
Monika KORDUS, Borys KOWALEWSKI
doaj   +1 more source

The Fight Against Colorism in the Black Community [PDF]

open access: yes, 2017
Since centuries ago African Americans have experienced discrimination more times than any other minority group. In 1983, Alice Walker introduced the term colorism which is, prejudice or discrimination against individuals with a dark skin tone, typically ...
Harris, Jeffrey
core  

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

open access: yesFEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää   +2 more
wiley   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

The Mora Obstruent /Q/ as an Emphatic in Japanese [PDF]

open access: yes, 2004
Introduction: Modern Japanese (ModJ) is a pitch accent language and its basic unit is the mora. Anaccented mora carries a high tone, with the subsequent mora carrying a low tone.
Irwin Mark
core   +1 more source

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

The impact of stress, anxiety and depression on stomatognathic system of physiotherapy and dentistry first‐year students

open access: yesBrain and Behavior, 2020
Introduction It is well proven that psychoemotional factors play causative role in development of many civilization diseases. Psychosocial stress is effecting with development of certain oral parafunctions like teeth grinding, bruxism, or cheeks biting ...
Joanna Elżbieta Owczarek   +2 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

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