Results 71 to 80 of about 863,837 (323)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Some Aspects of Printing Quality [PDF]

open access: yes, 1959
The object of this experiment was to find the effect of various pressures upon the ink coverage and the visual appearance of the half-tone print. A specially designed plate with four evenly spaced elevations was used with a Vandercook proof press ...
Badger, Robert B., Jr.
core   +1 more source

KEKUATAN KATA SEBAGAI PEMBANGUN KARAKTER REMAJA [PDF]

open access: yes, 2017
Building characters is very important for a nation’s future. Teenagers as the next generation become our awareness or focus in it. Parents, teachers and societies have responsibilities to build their teenagers’ characters.
Suwarti, Fransisca
core   +3 more sources

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Circadian Distribution and Autonomic Tone Modulation in Paroxysmal Atrial Fibrillation

open access: yesJournal of Arrhythmia, 2008
Understanding the role played by autonomic tone changes in the initiation of paroxysmal atrial fibrillation (PAF. may be helpful in preventing the occurrence of the arrhythmia.
Teruhisa Tanabe
doaj   +1 more source

How To Study a Tone Language [PDF]

open access: yes, 2014
In response to requests I have often got as to how one approaches a tone language, I present a personal view of the three stages involved, starting from scratch and arriving at an analysis: Stage I: Determining the tonal contrasts and their approximate ...
Hyman, Larry
core  

Time Domain Computation of a Nonlinear Nonlocal Cochlear Model with Applications to Multitone Interaction in Hearing

open access: yes, 2002
A nonlinear nonlocal cochlear model of the transmission line type is studied in order to capture the multitone interactions and resulting tonal suppression effects.
Deng, Li, Qi, Yingyong, Xin, Jack
core   +1 more source

"Who Are We? Where Are We?": Contact and Literary Navigation in The Maine Woods [PDF]

open access: yes, 2012
This essay argues that Thoreau witnesses a series of clashes across the three essays collected in "The Maine Woods" and that Thoreau positions himself with a variety of contact zones, enabling him both to navigate the landscapes of northern Maine and ...
James S. Finley
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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