Results 91 to 100 of about 269,296 (282)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Sensor and Display Human Factors Based Design Constraints for Head Mounted and Tele-Operation Systems

open access: yesSensors, 2011
For mobile imaging systems in head mounted displays and tele-operation systems it is important to maximize the amount of visual information transmitted to the human visual system without exceeding its input capacity.
Ralph Etienne-Cummings   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Sonification as a possible stroke rehabilitation strategy

open access: yesFrontiers in Neuroscience, 2014
Despite cerebral stroke being one of the main causes of acquired impairments of motor skills worldwide, well-established therapies to improve motor functions are sparse.
Daniel S. Scholz   +6 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Using Adaptive Tone Mapping to Enhance Edge-Preserving Color Image Automatically

open access: yesEURASIP Journal on Image and Video Processing, 2010
One common characteristic of most high-contrast images is the coexistence of dark shadows and bright light source in one scene. It is very difficult to present details in both dark and bright areas simultaneously on most display devices.
Lu Min-Yao   +4 more
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

SINGLE EXPOSURE VS TONE MAPPED HIGH DYNAMIC RANGE IMAGES: A STUDY BASED ON QUALITY OF EXPERIENCE [PDF]

open access: yes, 2014
International audienceTone mapping operators (TMOs), employed to fit the dynamic range of High Dynamic Range (HDR) visual signals to that of the display, are generally non-transparent and modify the visual appearance of the scene.
Le Callet, Patrick   +3 more
core   +1 more source

Learning High Dynamic Range from Outdoor Panoramas

open access: yes, 2017
Outdoor lighting has extremely high dynamic range. This makes the process of capturing outdoor environment maps notoriously challenging since special equipment must be used. In this work, we propose an alternative approach. We first capture lighting with
Lalonde, Jean-François, Zhang, Jinsong
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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