Results 271 to 280 of about 1,017,088 (353)

Single GAF Domain Phytochrome Exhibits a pH‐Dependent Shunt on the Millisecond Timescale

ChemPhysChem, Volume 26, Issue 6, March 15, 2025.
During their light‐induced photocycle, phytochromes can engage in a thermal reversion back to the initially excited state, denoted as a shunt. This study investigates a pH‐dependent shunt transition in the Pfr state of the All2699g1 phytochrome from Nostoc punctiforme using UV/Vis laser flash photolysis and kinetic modeling. The findings suggest a keto‐
Florian Trunk, Lisa Köhler, Tobias Fischer, Wolfgang Gärtner, Chen Song, Chavdar Slavov, Josef Wachtveitl   +6 more
wiley   +1 more source

Causal relationship between circulating lipid metabolism biomarkers and tongue cancer: A two-sample Mendelian randomization study. [PDF]

Medicine (Baltimore)
Meng X, Shen K, Fan J, Zhang J, Ma J, Li X, Wang Y.   +6 more
europepmc   +1 more source

Recommended Phase II Doses of Talquetamab in Patients With Relapsed/Refractory Multiple Myeloma From MonumenTAL‐1: Clinical Pharmacology Results

Clinical Pharmacology &Therapeutics, EarlyView.
Talquetamab is the first and only GPRC5D × CD3 bispecific antibody approved for relapsed/refractory multiple myeloma (RRMM). In the phase I/II MonumenTAL‐1 study, overall response rates (ORRs) were > 66% in patients with RRMM treated with subcutaneous talquetamab at the recommended phase II doses (RP2Ds): 0.4 mg/kg weekly and 0.8 mg/kg every other week.
Jue Gong, Jie Zhou, Dongfen Yuan, Xuewen Ma, Deeksha Vishwamitra, Brandi Hilder, Tara J. Masterson, Jaszianne Tolbert, Thomas Renaud, Christoph Heuck, Colleen Kane, Mahesh N. Samtani, Suzette Girgis, Nahor Haddish‐Berhane, Jesus Berdeja, Amrita Krishnan, Daniele Ouellet   +16 more
wiley   +1 more source

Associations of tongue and hyoid position, tongue volume, and pharyngeal airway dimensions with various dentoskeletal growth patterns. [PDF]

PLoS One
Kang JH, Kim JY, Jha N, Jung SK, Lee YS, Kim YJ.   +5 more
europepmc   +1 more source

Fifty years of research on the Joulters ooid sandbody—Impact on carbonate sedimentology and diagenesis and lessons learned from an invaluable analogue

The Depositional Record, EarlyView.
The Joulters ooid sandbody of northern Great Bahama Bank is a vast expanse of muddy ooid sands partly rimmed by clean ooid sands and formed into a relatively thick layer of significant extent. Knowledge of the development of depositional and diagenetic patterns in the Joulters example has forwarded our general understanding of carbonate sedimentology ...
Harris (Mitch) Paul
wiley   +1 more source

Bahaman patch reefs: Numerous and neglected

The Depositional Record, EarlyView.
Abstract Phanerozoic patch reefs are extensively studied because they are abundant and are potential reservoirs for valuable fluids. In contrast, geologic studies of modern reefs have largely focused on platform margins, leaving patch reefs comparatively neglected. What conditions favour patch‐reef development?
Paul Enos, Clay Robertson
wiley   +1 more source

A Novel Approach to the Study of Pathophysiology in Patients with Obstructive Sleep Apnea Using the Iowa Oral Performance Instrument (IOPI). [PDF]

J Clin Med
Navarro A, Bosco G, Serrano B, Baptista P, O'Connor-Reina C, Plaza G.   +5 more
europepmc   +1 more source

A head start: The relationship of placental factors to craniofacial and brain development

Developmental Dynamics, EarlyView.
Abstract In recent years, the importance of placental function for fetal neurodevelopment has become increasingly studied. This field, known as neuroplacentology, has greatly expanded possible etiologies of neurodevelopmental disorders by exploring the influence of placental function on brain development.
Annemarie Jenna Carver, Martine Dunnwald, Hanna Elizabeth Stevens   +2 more
wiley   +1 more source