Results 41 to 50 of about 103,994 (249)

A Biomimetic Dual‐Targeting Nano‐APA‐Editor Reprograms the 3'UTR Landscape for Tongue Squamous Cell Carcinoma Therapy

Advanced Science, EarlyView.
This study unveils a pathogenic axis in oral cancer where NUDT21 suppresses a tumor suppressor network, prominently PTEN, via 3'UTR lengthening. To exploit this transcriptomic vulnerability, we developed a biomimetic Nano‐APA‐editor. By delivering CRISPR/Cas9, we reprogrammed the global 3'UTR landscape, restoring multi‐target tumor suppression and ...
Yiran Ao, Bin Gu, Hui Zhao, Kun Tan, Qin Zhao, Zhengjun Shang   +5 more
wiley   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

Tongue Image Segmentation Method Based on the VDAU-Net Model

IEEE Access
Accurate segmentation of the tongue is fundamental to tongue diagnosis, yet existing methods are predicated on images captured under standard conditions. In practical tongue diagnosis, such controlled environments are not always feasible.
Fengdong Shi, Tongtong Liang, Song Cui
doaj   +1 more source

Morbidity Among the Aging Population in Northern Bangladesh: An Epidemiological Study

AGING MEDICINE, EarlyView.
Multimorbidity (≥ 2 chronic diseases) is common among aging populations, yet evidence from Bangladesh remains limited. A cross‐sectional survey of 540 older adults in Northern Bangladesh (June–August 2022) assessed multimorbidity using interviews and logistic regression analysis. Multimorbidity prevalence was 75.74% (95% CI: 71.9%–79.3%).
Md. Abu Sayem, Md. Golam Hossain, Md. Mothashin, Md. Nurul Islam   +3 more
wiley   +1 more source

Constructing an Artificial Intelligent Deep Neural Network Battery for Tongue Region Segmentation and Tongue Characteristic Recognition

World Journal of Traditional Chinese Medicine
Objective: This study aimed to construct a two-stage deep learning framework to segment and recognize tongue images and enhance the accuracy and efficiency of artificial intelligence (AI) tongue diagnosis in traditional Chinese medicine (TCM).
Tian-Xing Yi, Jian-Xin Chen, Xue-Song Wang, Meng-Jie Kou, Qing-Qiong Deng, Xu Wang   +5 more
doaj   +1 more source

Clinical utility of pharyngeal high‐resolution manometry with impedance for upper esophageal sphincter dysfunction in gastroenterology

Advances in Digestive Medicine, EarlyView.
Abstract Pharyngeal high‐resolution manometry with impedance (P‐HRM‐I) is an established assessment method used to evaluate pharyngeal swallowing. It provides precise quantification of swallowing biomechanics that enable the detection of alterations in swallowing physiology.
Mistyka Schar, Taher Omari, Michal Szczesniak, Chien‐Lin Chen, Richard Heddle, Charles Cock   +5 more
wiley   +1 more source

Smart Flexible Tactile Sensors: Recent Progress in Device Designs, Intelligent Algorithms, and Multidisciplinary Applications

Advanced Intelligent Discovery, EarlyView.
Flexible tactile sensors have considerable potential for broad application in healthcare monitoring, human–machine interfaces, and bioinspired robotics. This review explores recent progress in device design, performance optimization, and intelligent applications. It highlights how AI algorithms enhance environmental adaptability and perception accuracy
Siyuan Wang, Ming Dong, Rongrong Bao, Caofeng Pan   +3 more
wiley   +1 more source

A Lethal Progressive Neuroinflammation Disguised as MOGAD Revealing a Final Diagnosis of Griscelli Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
Chiara Veredice, Chiara Arpaia, Ilaria Contaldo, Anna Capasso, Donato Rigante   +4 more
wiley   +1 more source

Intelligent tongue diagnosis model for gastrointestinal diseases based on tongue images

Biomedical Signal Processing and Control
Xu Qiao, Chenyang Lu, Zhiping Liu
exaly   +2 more sources

Cysticercosis of tongue: Cytohistologic approach to diagnosis

Journal of Oral and Maxillofacial Pathology, 2013
Cysticercosis is continuing to be a major health problem in developing countries. Radiological and serological techniques are routinely used for pre-operative diagnosis of cysticercosis. But fine needle aspiration cytology (FNAC) is cost effective and simple procedure, so it is important to be aware of diagnostic pitfalls in the cytomorphologic ...
Koteeswaran, Govindaswamy, Mangala, Goneppanavar, Kotasthane, Dhanajay Srikant, Tirou, Aroul T   +3 more
openaire   +3 more sources