Results 91 to 100 of about 2,338,700 (302)

Rare diseases and orphan drugs: Latvian story [PDF]

open access: yes, 2014
Publisher Copyright: © 2014 Logviss et al.; licensee BioMed Central Ltd.Background: Ten years have passed since Latvia became a Member State of the EU in 2004.
Logviss, Konstantins   +2 more
core   +1 more source

Prenatal Evaluation of RNU4‐2 Variants in Fetuses With Central Nervous System Anomalies

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Fetal central nervous system (CNS) anomalies are among the most common congenital malformations, yet the overall prenatal diagnostic yield of current genetic testing remains below 40%. Variants in RNU4‐2, a non‐coding gene encoding the U4 small nuclear RNA (snRNA), have recently been linked to a novel highly recurrent dominant ...
Yiyao Chen   +13 more
wiley   +1 more source

Structural disturbance and reconstruction of glossectomy patients

open access: yes, 2012
The tongue is a complex muscular organ that can alter greatly in shape. This ability to change form is directly derived from its complex architecture which consists of interweaving but distinct muscle groups.
To, VSH, Wong, STS
core  

Laser Photocoagulation of Tongue Hemangioma: Case Report [PDF]

open access: yes, 2013
This report describes two cases of tongue hemangioma and shows the effectiveness of photocoagulation with diode laser. A thirty-five year-old female patient with a tongue hemangioma measuring 20x30 mm was referred.
Remzi Doğan   +4 more
core   +1 more source

Zebrafish xenograft models as a fast platform for metastasis diagnosis and cisplatin response of head and neck squamous cell carcinoma

open access: yesAnimal Models and Experimental Medicine, EarlyView.
A zebrafish xenograft model accurately distinguishes metastatic from non‐metastatic HNSCC and recapitulates cisplatin sensitivity/resistance patterns. Using patient‐derived tumors, it predicts individual therapeutic responses, offering a rapid, clinically applicable platform for guiding personalized treatment. Abstract Background Head and neck squamous
Lu Chen   +11 more
wiley   +1 more source

Tip of the tongue diagnosis: Tongue signs in neurological diseases [PDF]

open access: yes
The tongue is a crucial organ with multiple roles in speech, taste, and overall oral function. Its complex anatomy and rich innervation make it an important site for detecting signs of systemic and neurological diseases.
Affonso, Amanda   +2 more
core  

A self‐retaining mouth prop for intraoral access during periodontal surgery in rat models: A technical note

open access: yesAnimal Models and Experimental Medicine, EarlyView.
A mouth prop designed to mimic the oral cavity of rats was made that provided stable, self‐retaining retraction, thereby facilitating oral surgery on rodents. Compared to conventional methods, it decreased surgical time, operator fatigue, and slippage. Its use led to higher efficiency and fewer complications and it was cost effective to produce.
Saravanan Sampoornam Pape Reddy   +5 more
wiley   +1 more source

Tooth row allometry in domestic rabbits and nondomestic lagomorphs: Evidence for a decoupling of body and tooth row size changes in evolutionary time

open access: yesThe Anatomical Record, EarlyView.
Domestic rabbits of different body sizes differ disproportionately in the length of their tooth row or the length of their diastema. Abstract In various domestic mammals, smaller breeds tend to have proportionally larger teeth, whereas this is not a universal trend across mammals.
Ursina L. Fasciati   +3 more
wiley   +1 more source

Monitoring pharmacodynamic and molecular drug targets in liquid biopsy: Exploratory study in liver cancer with modelling of EGFR Receptor engagement

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Liquid biopsy is minimally invasive (compared with tissue biopsy) and has previously been used to generate systems data regarding drug elimination via hepatic enzymes and transporters. This study extends quantitative assessment of systems parameters in liquid biopsy to pharmacodynamic (PD) and disease markers relevant to cancer development
Zubida M. Al‐Majdoub   +3 more
wiley   +1 more source

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