Results 251 to 260 of about 493,766 (351)

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

open access: yesThe FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou   +4 more
wiley   +1 more source

Rare Case of Tongue Metastasis From Lung Adenocarcinoma, With White Coating Appearance. [PDF]

open access: yesRespirol Case Rep
Morimoto T   +9 more
europepmc   +1 more source

Safety and Efficacy of Vadadustat Versus Darbepoetin Alfa for Chronic Kidney Disease–Related Anemia in Patients Receiving Dialysis by Baseline Erythropoiesis‐Stimulating Agent Dose

open access: yesHemodialysis International, EarlyView.
ABSTRACT Introduction Erythropoiesis‐stimulating agents (ESAs) and iron supplementation are standard treatments for chronic kidney disease (CKD)–related anemia. Targeting higher hemoglobin values in CKD increases cardiovascular risk. Whether the increased risk is from higher ESA doses or higher hemoglobin levels is uncertain, but alternative therapies ...
Alan Jardine   +9 more
wiley   +1 more source

CDKN2A deletion in p16‐negative/HPV‐positive head and neck squamous cell carcinoma: Highlighting the molecular basis behind the limitation of relying on p16 immunohistochemistry as a surrogate marker for HPV involvement

open access: yesHistopathology, EarlyView.
We present a case series of HPV‐positive non‐keratinizing squamous cell carcinoma of the head and neck with discordant negative p16 staining due to CDKN2A deletion. These findings highlight the genomic basis behind the diagnostic pitfall of reliance on p16 immunohistochemistry as a surrogate marker of HPV and raise practice‐changing considerations for ...
Trevor Teich   +8 more
wiley   +1 more source

Sex Differences in Health‐Related Quality of Life in Patients With Head and Neck Cancer—A Prospective Study

open access: yesInternational Journal of Dental Hygiene, EarlyView.
ABSTRACT Objective To analyse sex differences in health‐related quality of life (HRQL) before, during and up to 3 months posttreatment of head and neck cancer, and to examine the importance of salivary secretion rate for HRQL posttreatment. Methods Patients were recruited before starting curative oncologic treatment.
Niklas Bohm   +4 more
wiley   +1 more source

Dermatologic Features of Endocrine Tumor Syndromes—Systematic Review and Meta‐Analysis

open access: yesInternational Journal of Dermatology, EarlyView.
ABSTRACT Endocrine tumor syndromes, including multiple endocrine neoplasia types 1, 2A, and 2B (MEN1, MEN2A, MEN2B), Carney complex (CNC), and PTEN hamartoma tumor syndrome (PHTS), are hereditary conditions characterized by multisystem tumor development.
Sára Pálla   +8 more
wiley   +1 more source

Prevalence, Characteristics, and Predictive Factors of Dentoalveolar and Spreading Odontogenic Infections in Children Treated Under General Anaesthesia

open access: yesInternational Journal of Paediatric Dentistry, EarlyView.
ABSTRACT Background Children receiving dental treatment under general anesthesia (GA) often have odontogenic infections (OIs). Early detection and treatment of patients at risk of OIs can improve oral health and prevent early tooth extractions. Aim To investigate the prevalence, characteristics, and predictive factors of OIs in children receiving ...
Annmari Hyppänen   +4 more
wiley   +1 more source

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