Results 81 to 90 of about 480,155 (368)

Neoadjuvant Chemotherapy With Cisplatin Up‐Regulates GSDMD to Enhance Oral Squamous Cell Carcinoma Metastasis Through MMP14‐Mediated EMT Activation

open access: yesAdvanced Science, EarlyView.
Oral squamous cell carcinoma cells exhibit upregulated expression of GSDMD upon exposure to low‐dose cisplatin chemotherapy, which subsequently interacts with MMP14 through its N‐terminal domain, activating the epithelial‒mesenchymal transition (EMT) process and promoting the lymph node metastasis of oral squamous cell carcinoma.
Zixian Huang   +9 more
wiley   +1 more source

Oral cancer in the UK: to screen or not to screen. [PDF]

open access: yes, 1998
Although oral squamous cell carcinoma accounts for only a small proportion of malignant neoplasms in the UK, oral cancer incidence and mortality rates have been rising in recent years.
Rodrigues, Veena
core  

Oral soft tissue biopsies in Oporto, Portugal: an eight year retrospective analysis [PDF]

open access: yes, 2015
Background: The diseases that affect the oral cavity are wide and diverse, comprising a broad spectrum of either benign or malignant lesions. However, few histological-based studies were performed for the evaluation of oral cavity lesions,
Albuquerque, Rui   +6 more
core   +2 more sources

Inhibiting FAT1 Blocks Metabolic Bypass to Enhance Antitumor Efficacy of TCA Cycle Inhibition through Suppressing CPT1A‐Dependent Fatty Acid Oxidation

open access: yesAdvanced Science, EarlyView.
This study demonstrates that mutant FAT1 promotes ASCL2‐driven, CPT1A‐dependent fatty acid oxidation, leading to resistance to CPI‐613‐mediated TCA cycle inhibition in head and neck cancer. In vivo gene depletion of mutant FAT1 with LNP‐sgFAT1 suppresses tumor growth and restores CPI‐613 sensitivity, revealing a targetable metabolic bypass with ...
Fanghui Chen   +11 more
wiley   +1 more source

A case of congenital neurovascular hamartoma with midline cleft of the upper lip

open access: yesJournal of Cleft Lip Palate and Craniofacial Anomalies, 2021
Developmental hamartomas are dysmorphic proliferation of native tissues which unlike neoplasms do not grow continuously and are mostly seen in infancy and childhood. Hamartoma of neurovascular origin can present itself as upper lip malformation.
Siddhartha Chatterjee   +2 more
doaj   +1 more source

Head and Neck Cancer Trends in Semarang: An analysis of ASR and ASCR [PDF]

open access: yes, 2015
Background: The sustainable incidence data of Head and Neck Cancer is poorly described in Indonesia. There was no large-scale epidemiological study of head and neck cancer in Indonesia, especially in Semarang and surrounding areas.
Hidanti, Mazaya Luthfia, PRASETYO, AWAL
core   +1 more source

Spatiotemporal Adaptations‐Driven Dynamic Thra Activation Simulates a Skin Wound Healing Response

open access: yesAdvanced Science, EarlyView.
This study uncovers the thyroid hormone receptor Thra as a pivotal regulator that spatiotemporally orchestrates dual‐phase skin repair. Epidermal Thra accelerates barrier restoration via glutathione‐driven keratin assembly, while dermal Thra establishes angiogenic niches through SAA3‐FN1‐mediated matrix remodeling.
Zeming Li   +15 more
wiley   +1 more source

A densidade do linfonodo metastático como fator prognóstico no carcinoma espinocelular da língua e soalho bucal The density of metastatic lymph node as prognostic factor in squamous cell carcinoma of the tongue and floor of the mouth

open access: yesBrazilian Journal of Otorhinolaryngology, 2012
A presença de linfonodos metastáticos é aspecto relevante no prognóstico do câncer bucal. OBJETIVO: Avaliar a densidade do linfonodo metastático (pN+) em pacientes com carcinoma espinocelular (CEC) de língua e soalho bucal e sua relação com a sobrevida ...
Ali Amar   +5 more
doaj   +1 more source

Lipid droplet detection by the cavity perturbation method [PDF]

open access: yes, 2011
There are currently no point-of-care diagnosis strategies available to indicate the presence of neoplasmic growth. This research aims to develop a novel diagnostic strategy based on detecting TAG accumulation in cells.
A I Al-Shamma'a   +7 more
core   +1 more source

PET/CT in the Staging and Treatment Response Assessment of Patients With Extranodal Marginal Zone Lymphoma

open access: yesAmerican Journal of Hematology, EarlyView.
Extranodal marginal zone lymphoma (EMZL) is essentially an FDG‐avid disease. PET/CT improves the precision in the response assessment compared to contrast‐enhanced CT. ABSTRACT 18Fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) is the standard imaging modality in lymphoma.
Juan Pablo Alderuccio   +10 more
wiley   +1 more source

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