Results 231 to 240 of about 27,403 (299)

XIAP Stabilizes DDRGK1 to Promote ER‐Phagy and Protects Against Noise‐Induced Hearing Loss

Advanced Science, EarlyView.
Mechanism of GAS‐mediated protection against noise‐induced hearing loss (NIHL). Noise exposure activates the ATF4/eIF2α axis, downregulating XIAP and promoting DDRGK1 degradation, thereby inhibiting ER‐phagy and leading to hair cell (HC) death. GAS treatment rescues XIAP and DDRGK1 expression, reactivating ER‐phagy to mitigate HC loss, synaptic damage,
Lin Yan, Yuhua Zhang, Jiawei Du, Yongjun Zhu, Wei Cao, Yongjie Wei, Han Wu, Shiyu Qiu, Shiyi Pan, Lian Chen, Pingping Liang, Renjie Chai, Jianming Yang, Qiaojun Fang   +13 more
wiley   +1 more source

Review Of The Problem Of Life By C. U. M. Smith [PDF]

, 1977
Jenkins, John B.
core   +1 more source

Transplantation of GABAergic Interneuron Progenitors Restores Cortical Circuit Function in an Alzheimer's Disease Mouse Model

Advanced Science, EarlyView.
Transplantation of medial ganglionic eminence (MGE) interneuron progenitors into APP/PS1 cortices restored the slow oscillation characteristic of Alzheimer's disease. Donor cells survived, migrated, and matured into functional GABAergic interneurons, forming synaptic connections.
Shinya Yokomizo, Megi Maci, April M. Stafford, Morgan R. Miller, Stephen J. Perle, Shuzo Inagaki, Shusaku Takahashi, Heather Brown‐Harding, Linda Liang, Alex Lovely, Moustafa Algamal, Rebecca L. Gillani, Theodore J. Zwang, Douglas Richardson, Janice R. Naegele, Daniel Vogt, Ksenia V. Kastanenka   +16 more
wiley   +1 more source

The Locus Coeruleus-Noradrenergic System in the Healthy and Diseased Brain: A Narrative Review. [PDF]

Eur J Neurol
Caestecker S, Lescrauwaet E, Boon P, Carrette E, Raedt R, Vonck K.   +5 more
europepmc   +1 more source

Contribution of Gli1+ Adventitial Stem Cells to Smooth Muscle Cells in Atherosclerosis and Vascular Injury

Advanced Science, EarlyView.
Gli1+ adventitial stem cells (ASCs) have been thought to generate smooth muscle cells (SMCs) in atherosclerosis. Using a dual‐recombinase lineage tracing to exclude ectopic labeling, Wang et al. found that Gli1+ ASCs do not contribute to SMCs in atherosclerotic plaques.
Haixiao Wang, Xiuzhen Huang, Jialing Mou, Enci Wang, Yan Li, Wenjuan Pu, Yao Xie, Xiaoling Guo, Lixin Wang, Maoping Chu, Bin Zhou, Chao Niu   +11 more
wiley   +1 more source

REM sleep quality is associated with balanced tonic activity of the locus coeruleus during wakefulness. [PDF]

J Biomed Sci
Mortazavi N, Talwar P, Koshmanova E, Sharifpour R, Beckers E, Berger A, Campbell I, Paparella I, Balda F, Dardour Hamzaoui I, Berthomier C, Bastin C, Phillips C, Maquet P, Collette F, Zubkov M, Lamalle L, Vandewalle G.   +17 more
europepmc   +1 more source

4D Printing of Magnetically Responsive Shape Memory Polymers: Toward Sustainable Solutions in Soft Robotics, Wearables, and Biomedical Devices

Advanced Science, EarlyView.
Merging 4D printing with magneto‐responsive shape memory polymers opens new avenues for intelligent, reconfigurable systems. This review navigates cutting‐edge fabrication techniques, magnetic fillers, and smart polymer matrices, unveiling their potential in soft robotics, biomedical devices, and wearable tech.
Kiandokht Mirasadi, Mohammad Amin Yousefi, Liuchao Jin, Davood Rahmatabadi, Majid Baniassadi, Wei‐Hsin Liao, Mahdi Bodaghi, Mostafa Baghani   +7 more
wiley   +1 more source

PupEyes: An interactive Python library for eye movement data processing. [PDF]

Behav Res Methods
Zhang H, Jonides J.
europepmc   +1 more source

Noradrenergic therapies in neurodegenerative disease: from symptomatic to disease modifying therapy? [PDF]

Brain Commun
Durcan R, O'Callaghan C, Rowe JB.
europepmc   +1 more source

Pupil Trend Reflects Suboptimal Alertness Maintenance over 10 s in Vigilance and Working Memory Performance: An Exploratory Study. [PDF]

eNeuro
Yamashita J, Terashima H, Yoneya M, Maruya K, Oishi H, Kumada T.   +5 more
europepmc   +1 more source