Results 81 to 90 of about 5,881 (273)
A 17 Year Old With Developmental Delay Presenting With Increasing Confusion and Imbalance
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Methylmalonic acidemia is an autosomal recessive genetic disorder primarily caused by defects in methylmalonyl‐CoA mutase and cobalamin (vitamin B12) metabolism. These defects disrupt the tricarboxylic acid cycle and oxidative phosphorylation, leading to the abnormal accumulation of metabolic products such as methylmalonic acid, propionic acid,
Wei Zhao, Yingli Zhang, Hongliang Zheng
wiley +1 more source
TONIC AND PHASIC EFFECTS OF REWARD ON THE PUPIL
, 2022 The Locus Coeruleus (LC), a nucleus in the pons of the brainstem, plays a significant role in attention and cognitive control. Here we use an adapted auditory oddball paradigm, and measured the pupil dilation response, to provide a marker of LC ...
Iain Donald Gilchrist
core +2 more sources
A novel method for modeling tonic and phasic pupil dynamics in humans. [PDF]
Behav Res MethodsThe human pupil is a widely used physiological metric in psychology and neuroscience. Changes in pupil diameter (PD) are thought to reflect changes in locus coeruleus-norepinephrine (LC/NE) activity, which is associated with cognitive and behavioral ...
Mittner M, Groot JM.
europepmc +2 more sources
The effect of tonic and phasic tVNS stimulation mode on pupil dilation.
, 2022 Transcutaneous auricular Vagus Nerve Stimulation (tVNS or taVNS) is a non-invasive technique for electrical stimulation of the vagus nerve through its auricular branch in the cymba conchae of the ear.
Anna Marzecová, Lina Skora
core +1 more source
Prominent Movement Disorders in RNU2‐2‐Related Spliceosomopathy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Pediatric movement disorders often overlap with neurodevelopmental diseases, suggesting shared molecular mechanisms. Variants in small nuclear RNA (snRNA) genes encoding spliceosome components have recently been associated with neurodevelopmental disorders, termed “RNUopathies.” We analyzed genome sequencing data from 14 patients with ...
Magdalena Krygier +6 more
wiley +1 more source
, 2010 Today a tonic pupila non-syphilitic pupil that reacts poorly to light and slowly redilates-- is often labelled an Adies pupil, and the symptom complex of a tonic pupil with absent deep tendon reflexes as Adies ...
Michael Kelly-Sell; Grant T. Liu
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie +8 more
wiley +1 more source
, 2014 PowerPoint presentation covering tonic pupil, which is damage to ciliary ganglion or short posterior ciliary nerves.
Adesina, Ore-Ofe, MD
core
Arthritis Care &Research, EarlyView.People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley +1 more source
Altered pupil light and darkness reflex and eye-blink responses in late-life depression
BMC GeriatricsBackground Late-life depression (LLD) is a prevalent neuropsychiatric disorder in the older population. While LLD exhibits high mortality rates, depressive symptoms in older adults are often masked by physical health conditions.
Yao-Tung Lee +7 more
doaj +1 more source