Results 151 to 160 of about 903,926 (343)

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

An industrial organisation approach to the too-big-to-fail problem. [PDF]

open access: yes
This article suggests a reform of the organisation of money markets that would largely eliminate the risk of contagion. The notion of “systemically important institution” would be replaced by that of systemically important platform”. Such platforms would
Rochet, JC.
core  

Have commodity trading houses become "too big to fail" ? [PDF]

open access: yes, 2016
Commodity trading is very important on a global scale, because of the nature of its activity - moving raw material from a place where it is abundant to a place where it is needed.
Lopez, Anas, Piller, Robert
core  

Is healthcare in the United States too big to fail?

open access: gold, 2008
Rubin Minhas   +2 more
openalex   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

open access: yesFEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna   +4 more
wiley   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

open access: yesFEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian   +6 more
wiley   +1 more source

νΛMDM: A model for sterile neutrino and dark matter reconciles cosmological and neutrino oscillation data after BICEP2

open access: yesPhysics Letters B, 2014
We propose an ultraviolet complete theory for cold dark matter (CDM) and sterile neutrinos that can accommodate both cosmological data and neutrino oscillation experiments within 1σ level.
P. Ko, Yong Tang
doaj  

Academic medical centers: too big to fail. [PDF]

open access: yesClin Transl Sci, 2013
Feldman AM, DiSesa VJ, Kaiser LR.
europepmc   +1 more source

Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity

open access: yesFEBS Open Bio, EarlyView.
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang   +6 more
wiley   +1 more source

Regulating “Too Big to Fail” [PDF]

open access: yes, 2013
The Dodd-Frank Act does not provide sufficient protection against another major financial crisis. A better regulatory system would promote financial stability by correcting the key market failures that lead to excessive risk taking by Strategically ...
Pericak, Christopher, Smetters, Kent
core   +1 more source

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