Results 41 to 50 of about 28,348 (298)

California: A Failed State or Too Big to Fail? [PDF]

open access: yesCalifornia Journal of Politics and Policy, 2011
THE CALIFORNIA Journal of Politics & Policy Volume 3, Issue 2 California: Failed State or Too Big to Fail? John L. Korey California State Polytechnic University, Pomona Abstract This report will begin with a discussion of various reasons for the state’s crisis.
openaire   +5 more sources

occumb: An R package for site occupancy modeling of eDNA metabarcoding data

open access: yesPopulation Ecology, EarlyView.
This study introduces a new R package, occumb, for the convenient application of site occupancy modeling using environmental DNA (eDNA) metabarcoding data. We outline a data analysis workflow, including data setup, model fitting, model assessment, and comparison of potential study settings based on model predictions, all of which can be performed using
Keiichi Fukaya, Yuta Hasebe
wiley   +1 more source

How Does Moral Hazard Impact Critical Market Banking Performance?

open access: yesAmerican Business Review
The degree to which financial institutions form expectations of policy intervention despite their own risk appetites lies at the heart of macrofinancial regulations such as the Dodd-Frank and Consumer Protection Acts.
Corey J. M. Williams
doaj   +1 more source

DU “TOO BIG TO FAIL” AU “TOO BIG TO BELIEVE” QUAND L’EMPRUNT TRACE SA VOIE DANS LA TERMINOLOGIE FRANÇAISE DE LA CRISE BUDGÉTAIRE AMÉRICAINE [PDF]

open access: yesDiversitate si Identitate Culturala in Europa, 2016
Through online economic texts published in 2013 by the French press following the American Congress failure to pass a budget for 2014, we examine how loan terms have made their way in the French terminology of the American budget crisis.
Andrée AFFEICH
doaj  

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Traces of business cycles in credit-rating migrations. [PDF]

open access: yesPLoS ONE, 2017
Using migration data of a rating agency, this paper attempts to quantify the impact of macroeconomic conditions on credit-rating migrations. The migrations are modeled as a coupled Markov chain, where the macroeconomic factors are represented by ...
Dmitri Boreiko   +3 more
doaj   +1 more source

Origins of Too-Big-to-Fail Policy

open access: yesWorking paper (Federal Reserve Bank of Cleveland), 2017
This paper traces the origin of the too-big-to-fail problem in banking to the bailout of the $1.2 billion Bank of the Commonwealth in 1972. It describes this bailout and those of subsequent banks through that of Continental Illinois in 1984. Motivations behind the bailouts are described with a particular emphasis on those provided by Irvine Sprague in ...
George Nurisso, Edward Simpson Prescott
openaire   +3 more sources

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

The "Too Big To Fail" Problem

open access: yes, 2019
“Too big to fail” – or “TBTF” – is a popular metaphor for a core dysfunction of today’s financial system: the recurrent pattern of government bailouts of large, systemically important financial institutions. The financial crisis of 2008 made TBTF a household term, a powerful rhetorical device for expressing the widely shared discontent with the ...
Saule T. Omarova, Cornell Law Library
openaire   +2 more sources

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

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