Results 51 to 60 of about 903,926 (343)

Traces of business cycles in credit-rating migrations. [PDF]

open access: yesPLoS ONE, 2017
Using migration data of a rating agency, this paper attempts to quantify the impact of macroeconomic conditions on credit-rating migrations. The migrations are modeled as a coupled Markov chain, where the macroeconomic factors are represented by ...
Dmitri Boreiko   +3 more
doaj   +1 more source

Origins of Too-Big-to-Fail Policy

open access: yesWorking paper (Federal Reserve Bank of Cleveland), 2017
This paper traces the origin of the too-big-to-fail problem in banking to the bailout of the $1.2 billion Bank of the Commonwealth in 1972. It describes this bailout and those of subsequent banks through that of Continental Illinois in 1984. Motivations behind the bailouts are described with a particular emphasis on those provided by Irvine Sprague in ...
George Nurisso, Edward Simpson Prescott
openaire   +3 more sources

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Too big to fail: the transatlantic debate [PDF]

open access: yes
Although the United States and the European Union were bothseriously impacted by the financial crisis of 2007, the resulting policy debates and regulatory responses have differed considerably on the two sides of the Atlantic.
Morris Goldstein, Nicolas Véron
core   +4 more sources

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Optimal equity capital requirements for large Swiss banks

open access: yesSwiss Journal of Economics and Statistics, 2018
Ten years after the worst financial crisis of the post-war period, Switzerland has established a Too-Big-To-Fail (TBTF) framework. Under this framework, the two large Swiss banks are subject to substantial capital requirements.
Georg Junge, Peter Kugler
doaj   +1 more source

Capital adjustment process and credit growth of microfinance institutions: Evidence from Sub-Saharan Africa

open access: yesCogent Economics & Finance, 2022
The purpose of this study is twofold: First, we examine the capital adjustment process using a partial adjustment framework and second, we test whether capitalization impacts the credit growth of microfinance institutions (MFIs) through the deviation (i ...
Tilahun Aemiro Tehulu
doaj   +1 more source

Can Electricity Companies Be Too Big to Fail? [PDF]

open access: yesSSRN Electronic Journal, 2017
Abstract The 2008 financial crisis has drawn attention to the concept of “too big to fail” companies, more recently relabelled "system-critical" institutions, referring to situations where the actual or near-bankruptcy of a company threatens the future of a service essential to the functioning of society.
Ann van Ackere   +3 more
openaire   +8 more sources

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