Results 111 to 120 of about 10,706,028 (311)

Time Tools

Topics in Cognitive Science
AbstractMany core human activities require an understanding of time. To coordinate rituals, plan harvests and hunts, recall histories, keep appointments, and follow recipes, we need to grapple with invisible temporal structures like durations, sequences, and cycles. No other species seems to do this.
openaire   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

The Advanced BioTRIZ Method Based on LTE and MPV

Biomimetics
While BioTRIZ is widely employed in biomimetic design to facilitate creative ideation and standardize workflows, accurately formulating domain conflicts and assessing design schemes during critical stages—such as initial concept development and scheme ...
Zhonghang Bai, Linyang Li, Yufan Hao, Xinxin Zhang   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Predictive Modeling and Optimization of Hot Forging Parameters for AISI 1045 Ball Joints Using Taguchi Methodology and Finite Element Analysis

Metals
This study focused on optimizing the hot forging process for AISI 1045 medium carbon steel ball joints, which is crucial for enhancing both their mechanical properties and production efficiency. Traditional hot forging processes often face challenges due
Naiyanut Jantepa, Nattarawee Siripath, Surasak Suranuntchai   +2 more
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

A Dynamic Scheduling Method Combining Iterative Optimization and Deep Reinforcement Learning to Solve Sudden Disturbance Events in a Flexible Manufacturing Process

Mathematics
Unpredictable sudden disturbances such as machine failure, processing time lag, and order changes increase the deviation between actual production and the planned schedule, seriously affecting production efficiency. This phenomenon is particularly severe
Jun Yan, Tianzuo Zhao, Tao Zhang, Hongyan Chu, Congbin Yang, Yueze Zhang   +5 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Surface micromorphology of Si3N4 ceramic by rotating ultrasonic grinding based on fractal theory

Jin'gangshi yu moliao moju gongcheng
To study the surface morphology of Si3N4 ceramics using rotary ultrasonic grinding, changes in the surface morphology under different machining parameters were analyzed based on fractal theory.
Yongguo SUN, Wei WANG, Wenzhi LI, Hengju WEI, Shiliang WEI   +4 more
doaj   +1 more source