Results 81 to 90 of about 5,379,499 (310)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
, 2012 In 1984 Hugnes Tool Company celebrates its 75th anniversary.The first product developed by the Company was the rolling cutter rock bit.This 1984-85 consolidated catalog contains product and sevice information from eleven of the Company 's ...
Tool Company, Hughes
core
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
, 2016 The microstructure and properties of a 5 wt.% Cr cold work tool steel were studied after austenitisation at 1020°C, 1050°C or 1075°C followed by single, double and triple tempering treatments at 525°C.
Rehan, Arbab +3 more
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Research on cutting mechanism and process optimization method of gear skiving
Scientific ReportsThe cutting force and cutting temperature have a significant impact on the service life and durability of gear skiving cutters. Due to unreasonable design, the existing process parameters lead to dramatically nonuniform cutting force and cutting ...
Peng Wang +5 more
doaj +1 more source
A Method for Inspiring Radical Innovative Design Based on Cross-Domain Knowledge Mining
SystemsThe reasonable application of cross-domain knowledge tends to promote the generation of radical innovation. However, it is difficult to accurately capture the cross-domain knowledge needed for radical innovation.
Fei Yu +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Tool life prediction and management for an integrated tool selection system [PDF]
, 1996 In machining, it is often difficult to select appropriate tools (tool holder and insert), machining parameters (cutting speed, feed rate and depth of cut) and tool replacement times for all tools due to the wide variety of tooling options and the ...
Alamin, Bubakar B.
core
The SynchAADL2Maude Tool [PDF]
, 2012 SynchAADL2Maude is an Eclipse plug-in that uses Real-Time Maude to simulate and model check Synchronous AADL models. Synchronous AADL is a variant of the industrial modeling standard AADL that supports the modeling of synchronous embedded systems.
Kyungmin Bae +3 more
openaire +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source