Results 211 to 220 of about 226,170 (300)

Physics‐Constrained Constitutive Learning of Rate‐Limiting Timescales for Efficient Hydrogen‐Based Direct Reduction for Green Steel Making

Advanced Science, EarlyView.
A conversion‐resolved constitutive framework is developed for the hydrogen‐based direct reduction of iron oxide pellets. Effective reaction and transport timescales are inferred directly from measured trajectories and mapped against operating conditions, pellet architecture, and composition. The analysis reveals how late‐stage transport control emerges
Anurag Bajpai, Barak Ratzker, Pasquale Cavaliere, Dierk Raabe   +3 more
wiley   +1 more source

Role of recruitment bias in stepped-wedge cluster randomised controlled trials: a systematic review. [PDF]

BMJ Open
Yakimova A, Wiggins F, Kanaan M, Keding A, Torgerson D.   +4 more
europepmc   +1 more source

Integrated Single‐Cell and Spatial Analysis Reveals a Metabolic‐Immune Axis Driving Aortic Dissection

Advanced Science, EarlyView.
Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao, Huanjie Yang, Jiahui Yong, Xueting Chen, Qiang Zhao, Xueli Wu, Lei Yan, Li Pang, Fan Luo, Mengjun Yu, Shanshan Pan, Deyang Li, Rouxi Chen, Juan Wang, Zhensheng Dong, Fan Yang, Yue Wang, Yang Chen, Hongjian Zheng, Zhimin Yang, Zijie Wang, Karsten Kristiansen, Hui Peng, Xiaodong Fang, Juan Shen, Yining Yang   +25 more
wiley   +1 more source

<i>In vitro</i> impact of storage media on extracted teeth: Systematic review and meta-analysis of adhesive, mechanical, and crack-related outcomes. [PDF]

J Conserv Dent Endod
Keswani K, Aggarwal S.
europepmc   +1 more source

Light‐Switched Mesenchymal Stem Cells for In Situ Exosome Amplification in Craniofacial Bone Defect Reconstruction

Advanced Science, EarlyView.
Light‐switchable MSCs (MSC‐UCNPs) were constructed by intracellular incorporation of UCNPs. Upon 980 nm irradiation, UCNPs emitted localized ultraviolet light (365 nm), activating the ROS/HEXB/LAMP1 signaling pathway to suppress lysosome–multivesicular body fusion and thereby enhance exosome biogenesis. Embedded within an injectable hydrogel, MSC‐UCNPs
Tingting Wu, Yajing Liu, Shuman Wang, Xiaoming Bai, Luyun Zhang, Yuwei Liu, Zhiwen Fu, Chen Shi   +7 more
wiley   +1 more source

Needle knife therapy for cervical spondylotic radiculopathy: A systematic review and meta-analysis. [PDF]

World J Methodol
Zhang YM, Li RG, Zhang XH, Wang ZY, Xu HH, Li XF, Zhang ZW.   +6 more
europepmc   +1 more source

High‐Performance Prevascularized SHED‐Laden rGO@Hydrogel Achieves Optimized Diabetic Bone Defect Repair

Advanced Science, EarlyView.
A high‐performance 3D scaffold integrating rGO and SHEDs is developed to overcome impaired healing in diabetic bone defects. By driving extracellular matrix remodeling, rGO creates a pro‐angiogenic niche that significantly accelerates in vitro vascular network formation.
Can Zhang, Yiyuan Kang, Shulin Lai, Chunyi Wang, Guixin He, Kehui Jian, Suhan Yin, Xiner Tan, Xinru Zhou, Wenjing Liu, Fujian Zhao, Jia Liu, Longquan Shao   +12 more
wiley   +1 more source

Drug‐Induced Cuproptosis Defines the Therapeutic Window of Celecoxib in Intervertebral Disc Degeneration via the HSP90‐RBX1 Axis

Advanced Science, EarlyView.
This study reveals the dual role of celecoxib in intervertebral disc degeneration. While low concentrations are protective, high concentrations induce toxicity by upregulating HSP90, which synergizes with USP15 to deubiquitinate and stabilize RBX1. This leads to degradation of COMMD1/ATP7B, copper dyshomeostasis, and ultimately, cuproptosis.
Youfeng Guo, Hongju Xiao, Shenghao Ba, Yu Zhou, Bijun Wang, Bin Yu, Yufeng Huang, Haihong Zhao, Zhefan Stephen Chen, Na Shen, Zhaoyu Ba, Desheng Wu   +11 more
wiley   +1 more source

Peer-led versus instructor-led debriefing in simulation-based interprofessional education (Sim-IPE) at a simulation centre in Qatar: protocol for a single-centre, parallel-group, non-inferiority randomised controlled trial. [PDF]

BMJ Open
El-Awaisi A, Mustafa DN, El Hajj MS, Major S, Brown M, Mahfoud ZR, O'Hara L, Elhage A, Al Hariri M.   +8 more
europepmc   +1 more source