Results 61 to 70 of about 872,163 (296)

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Cutting Force Mechanisms in Drilling 90MnCrV8 Tool Steel: ANOVA and Theoretical Insights

Journal of Manufacturing and Materials Processing
This study investigates the influence of tool geometry and cutting parameters on thrust forces and process stability during the drilling of 90MnCrV8, a hard and wear-resistant tool steel. The objective was to identify the dominant and interactive effects
Jaroslava Fulemová, Josef Sklenička, Jan Hnátík, Miroslav Gombár, Jindřich Sýkora, Michal Povolný, Adam Lukáš   +6 more
doaj   +1 more source

THE INFLUENCE OF THE TOOL POINT ANGLE AND FEED RATE ON THE DYNAMIC PARAMETERS AT DRILLING COATED PARTICLEBOARD [PDF]

Pro Ligno, 2015
Pre-laminated (coated) particleboards (PB) are wood-based composites intensively used in the furniture industry. In order to prepare the PB for joining, drilling is the most commonly applied machining process.
Mihai ISPAS, Sergiu RĂCĂŞAN
doaj  

Higher Amyloid and Tau Burden Is Associated With Faster Decline on a Digital Cognitive Test

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective A 2‐min digital clock‐drawing test (DCTclock) captures more granular features of the clock‐drawing process than the pencil‐and‐paper clock‐drawing test, revealing more subtle deficits at the preclinical stage of Alzheimer's disease (AD). A previous cross‐sectional study demonstrated that worse DCTclock performance was associated with
Jessie Fanglu Fu, Talia Robinson, Marina Rodriguez Alonso, Adela Francis Malave, Roos J. Jutten, Michael J. Properzi, Brian C. Healy, Jackson C. Thompson, Grace Del Carmen Montenegro, Emma Thibault, Dana Penney, Randall Davis, Reisa A. Sperling, Kathryn V. Papp, Keith A. Johnson, Julie C. Price, Dorene M. Rentz   +16 more
wiley   +1 more source

Deflection of Complex Geometry Cutting Tools [PDF]

Manufacturing Technology, 2017
Deflection of cutting tools under the action of cutting forces has a significant influence on the error of machined surface and the stability of cutting process. Considering the complex geometric structure of cutting tools lead to higher calculation accuracy of the tool deflection analysis.
Bílek, Ondřej, Smetka, Pavel, Baďurová, Jitka   +2 more
openaire   +1 more source

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu, Yuxi Gong, Weilin Xu, Xingjian Sun, Gefei Jiang, Lei Qiu, Kexin Shi, Mengxing Wu, Yinjiao Fei, Jinling Yuan, Jinyan Luo, Yurong Li, Yuandong Cao, Minhong Pan, Shu Zhou   +14 more
wiley   +1 more source

Effect of Different Tool Geometries in Friction Stir Welding of AA 2024-T3 using Design of Experiments

مجلة النهرين للعلوم الهندسية, 2017
In this work, Aluminum alloy (AA2024-T3) was welded by friction stir (FSW) method using different pin profile design types; straight cylinder, threaded cylinder, tapered cylinder hexagonal, square, and threaded taper.
Moneer H. Al-Saadi, Sabah Khammass Hussein, Mursal Luaibi Saad   +2 more
doaj  

Parametric Geometry 3D Sketch Tool [PDF]

, 2014
Cílem této práce je seznámení se s 3D parametrickými konstrukčními nástroji a jejich podporou dynamické geometrie. Práce obsahuje vymezení základních pojmů z oblasti parametrické konstrukce v souvislosti s dynamickou geometrií, shrnutí současného stavu ...
Vala, Jan
core  

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

FindGeo: a tool for determining metal coordination geometry [PDF]

Bioinformatics, 2012
Abstract Summary: Metals are essential for the structure and function of many proteins and nucleic acids. The geometrical arrangement of the atoms that coordinate a metal in a biological macromolecule is an important determinant of the specificity and role of that metal.
ANDREINI, CLAUDIA, CAVALLARO, GABRIELE, LORENZINI, SERENA   +2 more
openaire   +4 more sources