Results 41 to 50 of about 571,152 (309)
On high-speed turning of a third-generation gamma titanium aluminide [PDF]
, 2012 Gamma titanium aluminides are heat-resistant intermetallic alloys predestined to be employed in components suffering from high mechanical stresses and thermal loads.
A Beranoagirre +20 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Analysis of Tool Wear in GH4169 Material Milling Process
Lubricants, 2023 Nickel-based superalloy GH4169 is a material with strong mechanical properties and is difficult to process. In order to reduce tool wear during material processing and improve the workpiece surface processing quality, based on the finite element ...
Xueguang Li +3 more
doaj +1 more source
Reliability assessment of cutting tool life based on surrogate approximation methods [PDF]
, 2014 A novel reliability estimation approach to the cutting tools based on advanced approximation methods is proposed. Methods such as the stochastic response surface and surrogate modeling are tested, starting from a few sample points obtained through ...
Kolios, Athanasios +1 more
core +1 more source
The performance of modified jatropha-based nanofluid during turning process [PDF]
, 2021 The industry's extensive use of petroleum-based metalworking fluid (MWF) harms the environment and humans. The production of bio-based MWF, especially from crude jatropha oil (CJO), has therefore taken numerous initiatives.
Abdullah, H. +6 more
core +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Surface Characterisation Based Tool Wear Monitoring in Peripheral milling [PDF]
, 2008 The progress of surface metrology in the last decade has led to improved 3D characterisation of surfaces which offers the possibility of monitoring manufacturing operations to give highly detailed information regarding the machine tool condition.
DJ Whitehouse +11 more
core +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Lubricants, 2022 Tool wear behavior is mainly influenced by cutting parameters for a given tool–workpiece pair and cutting process. Rapid tool wear increases production costs and deteriorates machining quality in manufacturing industries.
Delin Liu, Zhanqiang Liu, Bing Wang
doaj +1 more source
Comparative Analysis and Monitoring of Tool Wear in Carbon Fiber Reinforced Plastics Drilling [PDF]
한국정밀공학회지, 2020 Recently, carbon fiber-reinforced plastic (CFRP) has been attracting much attention in various industries because of its beneficial properties such as excellent strength, modulus per unit density, and anti-corrosion properties. However, there are several
Kyeong Bin Kim +4 more
doaj +1 more source