Results 21 to 30 of about 72,439 (260)
Embedding Theory into Learning Technology Practice with Toolkits
Journal of Interactive Media in Education, 2002 : Expert and theoretical knowledge about the use of learning technology is not always available to practitioners. This paper illustrates one way in which practitioners can be supported in the process of engaging with theory in order to underpin practical
Grainne C. Conole, Martin Oliver
doaj +1 more source
User-centred design for machine learning in health care: a case study from care management
BMJ Health & Care Informatics, 2022 Objectives Few machine learning (ML) models are successfully deployed in clinical practice. One of the common pitfalls across the field is inappropriate problem formulation: designing ML to fit the data rather than to address a real-world clinical pain ...
Ron C Li +18 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
InformaticsThis study addresses the need to integrate ethical, human-centered principles into user experience (UX) design for generative AI (GenAI)-based assistants. Acknowledging the ethical and societal challenges posed by the democratization of GenAI, this study
Carlos Alberto Peláez +9 more
doaj +1 more source
Embodied and Embedded Theory in Practice: The Student-Owned Learning-Engagement (SOLE) Model
International Review of Research in Open and Distributed Learning, 2011 The demands on academic staff in all sectors to adopt best ODL practices to create effective and efficient models of learning in the face of increasing external pressures show no signs of abating. The massification of higher education, diversified access,
Simon Atkinson
doaj +3 more sources
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
A Compression-Based Toolkit for Modelling and Processing Natural Language Text
Information, 2018 A novel compression-based toolkit for modelling and processing natural language text is described. The design of the toolkit adopts an encoding perspective—applications are considered to be problems in searching for the best encoding of different ...
William John Teahan
doaj +1 more source
The Wearable Co-Design Domino: A User-Centered Methodology to Co-Design and Co-Evaluate Wearables
Sensors, 2020 This paper presents a user-centered methodology to co-design and co-evaluate wearables that has been developed following a research-through design methodology.
Leire Francés Morcillo +3 more
doaj +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
An Integrated Optical Circuit Architecture for Inverse-Designed Silicon Photonic Components
Sensors, 2023 In this work, we demonstrate a compact toolkit of inverse-designed, topologically optimized silicon photonic devices that are arranged in a “plug-and-play” fashion to realize many different photonic integrated circuits, both passive and active, each with
Dusan Gostimirovic, Richard Soref
doaj +1 more source