Results 101 to 110 of about 9,039,965 (305)

Research on chemical modification of nickel coating on diamond particles surface

open access: yesJin'gangshi yu moliao moju gongcheng
A new nickel plating process for diamond wire is explored to eliminate the negative impact of dispersants on the production process of diamond wires. The surface of of Ni-plated diamond particles was first hydroxylated with hydrogen peroxide, and then ...
Yuyao ZOU   +3 more
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Lunar hand tools [PDF]

open access: yes
Tools useful for operations and maintenance tasks on the lunar surface were determined and designed. Primary constraints are the lunar environment, the astronaut's space suit and the strength limits of the astronaut on the moon.
Bentz, Karl F.   +7 more
core   +1 more source

Methodological tools

open access: yes, 2012
Methodological approaches for comparing metabolic theory predictions to empirical data fall into two general categories: 1) determining if the general functional form of a relationship predicted by the theory is valid; and 2) determining whether the observed values of the parameters match the specific quantitative predictions made by the theory.
White, Ethan P.   +3 more
openaire   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Comparing tools for Service Quality Evaluation

open access: yes, 1998
Service quality evaluation is one of the main issues that have recently drawn managers' and researchers' attention. The definition of an evaluation standard not dependent on any particular service context has determined the popularity of many different ...
Caldara, M.   +2 more
core   +1 more source

Influence of the Substrate Size on the Cooling Behavior and Properties of the DED-LB Process

open access: yesJournal of Machine Engineering
The laser-based Directed Energy Deposition (DED-LB) process involves a complex thermal history which strongly de-pends on the geometry of the deposited structure and substrate.
Fabian Bieg   +2 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

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