Homologous expression and purification of human HAX‐1 for structural studies
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Technological innovations and hafted technology in central China ~160,000-72,000 years ago. [PDF]
Yue JP +16 more
europepmc +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Application of patient-reported outcomes in clinical trials of traditional Chinese medicine registered in international clinical trials registry platform, from 2010 to 2022: a cross-sectional study. [PDF]
Lin Y +10 more
europepmc +1 more source
Balancing speed and precision in protein folding: a comparison of AlphaFold2, ESMFold, and OmegaFold. [PDF]
Hýsková A +2 more
europepmc +1 more source
Benchmarking UMI clustering tools for accurate detection of low-frequency variants from deep sequencing. [PDF]
Pu D +6 more
europepmc +1 more source
The impact of generative AI on foreign language enjoyment: the roles of gender, English proficiency and usage duration among Chinese EFL learners. [PDF]
Yin X, Ruan J, Ma W.
europepmc +1 more source
Nursing Educators' Perceptions of AI in Research: Risks and Benefits. [PDF]
Mrayyan MT, Al-Omari AK.
europepmc +1 more source
How to design decision-support tools for primary healthcare using a human-centred design approach: the processes and experience of PHISICC in three Sub-Saharan countries. [PDF]
Rodriguez Franco D +16 more
europepmc +1 more source

