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METTL3 Promotes Osteo/Odontogenic Differentiation of Stem Cells by Inhibiting miR-196b-5p Maturation
Stem Cells International, 2023 Mesenchymal stem cells (MSCs) have been considered a potential method for the regeneration of tooth and maxillofacial bone defects based on the multidirectional differentiation characteristics of MSCs.
Xiao Han +7 more
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Advances of exosomes in periodontitis treatment
Journal of Translational Medicine, 2022 Periodontitis is an inflammatory disease initiated by dysbiosis of the local microbial community. Periodontitis can result in destruction of tooth-supporting tissue; however, overactivation of the host immune response is the main reason for alveolar bone
Hongbing Lin +8 more
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Dietary nitrate supplementation prevents radiotherapy-induced xerostomia
eLife, 2021 Management of salivary gland hypofunction caused by irradiation (IR) therapy for head and neck cancer remains lack of effective treatments. Salivary glands, especially the parotid gland, actively uptake dietary nitrate and secrete it into saliva.
Xiaoyu Feng +15 more
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Controls on dense-water formation along the path of the North Atlantic subpolar gyre [PDF]
Ocean ScienceThe North Atlantic subpolar gyre (SPG) plays a fundamental role in the global climate system through the formation of dense North Atlantic Deep Water (NADW) as part of the Atlantic Meridional Overturning Circulation.
O. J. Tooth +3 more
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Stem Cells International, 2020 Retinoic acid (RA) signal is involved in tooth development and osteogenic differentiation of mesenchymal stem cells (MSCs). Dental pulp stem cells (DPSCs) are one of the useful MSCs in tissue regeneration. However, the function of RA in osteo/odontogenic
Jiangyi Wang +9 more
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Effects of chronic stress caused by occlusal disorder on the body
口腔疾病防治, 2020 Occlusal disorder is an abnormal condition in which the static and dynamic relations between the upper and lower teeth are not well aligned . The most common occlusal disorder in clinical practice is the inability to reach the intercuspal position due to
JIANG Jiayang +6 more
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Data, 2017 Arctic sea ice has been on the decline over the past several decades, and multi-year sea ice has decreased significantly in its areal share of the overall sea ice cover.
Matthew Tooth, Mark Tschudi
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Stem Cell Research & Therapy, 2021 Background Unresolved inflammation and tissue destruction are considered to underlie the failure of dental pulp repair. As key mediators of the injury response, dental pulp stem cells (DPSCs) play a critical role in pulp tissue repair and regeneration ...
Jie Chen +4 more
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The impact of masticatory dysfunction caused by occlusal disharmony on cognitive function
口腔疾病防治, 2021 As the world’s population ages, age-related cognitive decline and dementia are becoming important challenges for geriatric care. Despite the ongoing search for solutions to address cognitive decline, effective interventions have not yet been established.
OU Yanzhen +5 more
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Tracking diphyodont development in miniature pigs in vitro and in vivo
Biology Open, 2019 Abnormalities of tooth number in humans, such as agenesis and supernumerary tooth formation, are closely related to diphyodont development. There is an increasing demand to understand the molecular and cellular mechanisms behind diphyodont development ...
Fu Wang +8 more
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