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Thermosensitive 2-Dg-Loaded Hydrogel Attenuates Periodontitis Via Th17 Suppression
Aim or purpose: To investigate the role of IL-17a in immune regulation during periodontitis and develop a novel localized drug delivery system based on glycolysis inhibition for safer and more effective treatment.
Ruowen Zhao, 俊豪 殷, 稼耀 傅
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Background Degenerative changes in the skeleton play an important role in ageing. As the foremost sensors and orchestrators of bone remodelling, osteocytes contribute significantly to the health of the skeleton. Embedded in a mineralized bone matrix, the
Chenyang Zhang +7 more
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Background Peri-implant inflammation is an important factor affecting the success rate of dental implants. Improving the antibacterial performance of implants is an effective method to prevent and treat peri-implant inflammation.
Keyi Wu +6 more
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As a series of attractive nanomaterials, nanozymes with great catalytic activity and specificity are well developed in the field of biosensors. Although promising, the lack of appropriate structural design strategy and limitation of sensing performance ...
Xiaocan Liu +9 more
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Background Excessive inflammation is a major cause of implant failure. The surface morphology, hydrophilicity, and loading of biomaterials are major properties modulating anti-inflammatory macrophage activation.
Xu Cao +6 more
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The patient-reported impact of Charcot-Marie-Tooth disease in the real world: the design and conduct of a digital lifestyle study (CMT&Me) [PDF]
Florian P. Thomas +17 more
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