Results 211 to 220 of about 58,228 (350)

Apremilast in Japanese patients with palmoplantar pustulosis: A randomized, Phase 3 trial

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
In this Phase 3 trial of Japanese patients with moderate to severe PPP (NCT05174065), significantly more patients achieved PPPASI‐50 at Week 16 with apremilast versus placebo. Patient‐reported outcomes, including pruritus and pain/discomfort, also showed significantly greater decreases at Week 16 with apremilast versus placebo.
Tadashi Terui   +15 more
wiley   +1 more source

Interdisciplinary Management of Open Interproximal Embrasures

open access: yesJournal of Esthetic and Restorative Dentistry, EarlyView.
ABSTRACT Objectives To describe key etiological and risk factors associated with open interproximal embrasures (OIE) and propose a systematic interdisciplinary approach for their management, emphasizing the integration of periodontics, orthodontics, and prosthodontics.
Yudai Ogawa   +7 more
wiley   +1 more source

Effect of Different Airborne‐Particle Abrasion Strategies on Dentin Bond Strength: An In Vitro Study

open access: yesJournal of Esthetic and Restorative Dentistry, EarlyView.
ABSTRACT Objective To assess the influence of dentin airborne‐particle abrasion techniques on the microtensile bond strength, using two adhesive strategies (self‐etch and etch&rinse). Materials and Methods Twenty molars were assigned to two groups (n = 10) according to the bonding system (Clearfil SE Bond or Optibond FL), divided into four parts and ...
Rui I. Falacho   +7 more
wiley   +1 more source

The “Reducing Inflammation for Greater Health Trial (RIGHT)” Study—Concept, Rationale, and Design

open access: yesJournal of the American Geriatrics Society, EarlyView.
ABSTRACT The Reducing Inflammation for Greater Health Trial's (RIGHT) study is a single‐center, randomized, double‐blind, placebo‐controlled trial designed to test whether clazkizumab, an interleukin‐6 (IL‐6) inhibitor, can improve or slow decline in physical, cognitive, and vascular function in older adults, when compared to a placebo.
Sebastian E. Sattui   +11 more
wiley   +1 more source

Mapping the murine TMJ glenoid fossa over development, homeostasis and in response to disease

open access: yesJournal of Anatomy, EarlyView.
The fibrocartilage of the murine glenoid fossa and condyle of the temporomandibular joint are shown to form at distinct times with distinct molecular identities. Changes in the condyle during disease lead to remodelling of the fossa to maintain joint alignment.
Ticha Tuwatnawanit   +4 more
wiley   +1 more source

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