Downregulation of FGF Signaling by Spry4 Overexpression Leads to Shape Impairment, Enamel Irregularities, and Delayed Signaling Center Formation in the Mouse Molar. [PDF]
FGF signaling plays a critical role in tooth development, and mutations in modulators of this pathway produce a number of striking phenotypes. However, many aspects of the role of the FGF pathway in regulating the morphological features and the mineral ...
Ahn, Youngwook+8 more
core +1 more source
The tooth eruption and its abnormalities - A narrative review
Background: The process of tooth eruption is influenced by local, systemic, and genetic factors. Any disturbances in these factors might lead to abnormalities in the eruption of the tooth. Aim: The aim of this narrative review is to classify and discuss the eruption and its ...
K V Sai Charan+6 more
openaire +2 more sources
[Dens invaginatus tooth abnormality].
Dens invaginatus (dens in dente) is a dental anomaly caused by an invagination of the tooth surface during tooth development.
Herrmann Stich+2 more
openaire +3 more sources
Abnormality in the Morphogenesis of Tooth Development and Relationship with Orthodontic Deformities and Treatment Approaches [PDF]
In the process of odontogenesis, a disturbance in the formation of the epithelium and mesenchyme can be observed and this can be manifested by atypical forms of dental development. Such biological phenomena with altered morphology are as follows: dens invaginatus (DI), dens evaginatus (DE), talon cusps, and double teeth (DT) or connate teeth (fusion ...
Greta Roussanova Yordanova-Kostova+2 more
openaire +3 more sources
Open versus closed surgical exposure of canine teeth that are displaced in the roof of the mouth [PDF]
Background: Palatal canines are upper permanent canine (eye) teeth that have become displaced in the roof of the mouth. They are a frequently occurring anomaly, present in 2% to 3% of the population.
Bishara+9 more
core +1 more source
Deficiency of the zinc finger protein ZFP106 causes motor and sensory neurodegeneration [PDF]
Acknowledgements We are indebted to Jim Humphries, JennyCorrigan, LizDarley, Elizabeth Joynson, Natalie Walters, Sara Wells and the whole necropsy, histology, genotyping and MLC ward 6 teams at MRC Harwell for excellent technical assistance. We thank the
Abramov, Andrey Y.+28 more
core +3 more sources
Mitochondrial dynamics–fusion, fission, movement, and mitophagy–in neurodegenerative diseases [PDF]
Neurons are metabolically active cells with high energy demands at locations distant from the cell body. As a result, these cells are particularly dependent on mitochondrial function, as reflected by the observation that diseases of mitochondrial ...
Alexander+42 more
core +3 more sources
Transposição dentária: dois relatos de casos e revisão de literatura
Resumo em português não ...
Camila Alves Ferri+1 more
doaj +6 more sources
OPA1 mutation and late-onset cardiomyopathy: mitochondrial dysfunction and mtDNA instability. [PDF]
BackgroundMitochondrial fusion protein mutations are a cause of inherited neuropathies such as Charcot-Marie-Tooth disease and dominant optic atrophy.
Bers, Donald M+10 more
core +2 more sources
Genome-wide association study of primary tooth eruption identifies pleiotropic loci associated with height and craniofacial distances [PDF]
Twin and family studies indicate that the timing of primary tooth eruption is highly heritable, with estimates typically exceeding 80%. To identify variants involved in primary tooth eruption we performed a population based genome-wide association study ...
Alexei I. Zhurov+84 more
core +2 more sources