Results 161 to 170 of about 279,075 (293)

Dental Pulp Stem Cell‐Derived Intracellular Vesicles Inhibit OSCC by Delivering PTEN to Suppress PI3K/AKT/mTOR Signalling Pathway

Cell Proliferation, EarlyView.
DPSC‐IVs suppressed PI3K/AKT/mTOR signalling pathway by delivering PTEN to tumour cells, which reduced the expression of Bcl‐2 and elevated that of Bax. Meanwhile, DPSC‐IVs activated PINK1/Parkin mediated mitophagy, which further raised ROS levels.
Yu Luo, Qiang Qin, Wenting She, Xiangying Wang, Xiqin Li, Chenxuan Shu, Ruohan Li, Ziwei Li, Dongjie Fu, Yan He, Qingsong Ye   +10 more
wiley   +1 more source

Periodontitis‐Associated Circulating EVs Promote Colorectal Cancer Progression via Carnosine‐Mediated Acidosis Adaptation

Cell Proliferation, EarlyView.
This study identifies a link between periodontitis and CRC progression mediated by carnosine‐enriched circulating EVs. These EVs target the intestine and elevate tumour cell intracellular pH (pHi), which rescues lysosomal function. This process drives a transition from dysfunctional lysosomes to functional ones, promoting a high malignancy phenotype in
Ruoyi Wu, Zihan Cai, Hualing Sun, Haikun Yu, Bicheng Zhang, Chi Zhang, Yi Fan, Xiaoxuan Zhu, Yueqi Ni, Yu Cui, Kaixin Wang, Zhe Li, Xinyi Zhou, Qing He, Yanru Wu, Yufeng Zhang   +15 more
wiley   +1 more source

A bio-based superhydrophobic pit and fissure sealant for enhanced stability and anticaries application. [PDF]

Mater Today Bio
Chen X, Zhang X, Wang X, Zhang C, Lv Y, Zhu R, Cao Y, Li B, Zheng S.   +8 more
europepmc   +1 more source

Chromatin Remodeller BRD9 Orchestrates Odontoblastic Differentiation via Coordinating RUNX2‐KLF4

Cell Proliferation, EarlyView.
During odontoblast lineage commitment, the chromatin remodeller BRD9 acts as a critical epigenetic coordinator, orchestrating the chromatin landscape to facilitate synergistic binding of key transcription factors RUNX2 and KLF4 to target loci for odontogenesis.
Wenrui Zeng, Yuxiu Lin, Yongyan Gao, Delan Huang, Yuanyuan Li, Honglei Ruan, Guohua Yuan, Huan Liu, Zhi Chen   +8 more
wiley   +1 more source

Coadministration of fluoride, trimetaphosphate, and quercetin reduces dentin erosive wear in vitro. [PDF]

Clin Oral Investig
Gomes IMP, Delbem ACB, Martins TP, da Silva IF, Ferraresso LFOT, Capalbo LC, Buzalaf MAR, Monteiro DR, Pessan JP.   +8 more
europepmc   +1 more source

Hospital Visits Related to Head and Neck Injuries and Domestic Abuse: A Report From 2017 to 2024 in Saskatchewan, Canada

Dental Traumatology, EarlyView.
ABSTRACT Introduction Domestic abuse is a significant public health issue associated with physical harm and long‐term health consequences. Injuries involving the head, face, and oral region are among the most frequent physical manifestations, making oral and maxillofacial trauma a potentially critical indicator of abuse in clinical settings. This study
Ana Beatriz Cantao, Marissa Evans, Liran Levin   +2 more
wiley   +1 more source

Wire Syndrome Associated with Multistrand Orthodontic Retainers: A Proposed Etiopathogenic Concept. [PDF]

Dent J (Basel)
Dridi SM, Charavet C.
europepmc   +1 more source

Longitudinal Deterioration of Custom‐Made Mouthguard Fit During 12 Months of Use in Athletes: Implications for Traumatic Dental Injury Prevention

Dental Traumatology, EarlyView.
ABSTRACT Objectives To investigate longitudinal changes in fit and user‐reported outcomes of custom‐made ethylene vinyl acetate (EVA) mouthguards during 12 months of athletic use, and to explore implications for traumatic dental injury prevention. Methods This prospective 12‐month longitudinal observational study included 41 athletes using custom‐made ...
Arisa Sugimoto, Tomoya Gonda, Yoshinobu Maeda, Kazunori Ikebe   +3 more
wiley   +1 more source

Evaluation of bonding of clear aligner attachments on aesthetic crown materials: a systematic review of <i>in vitro</i> studies. [PDF]

Front Dent Med
Kaur A, Soans CR, Ravi MS, Shilpa M.
europepmc   +1 more source

Development and Evaluation of an Online Learning Tool for Undergraduate Education in Dental Traumatology

Dental Traumatology, EarlyView.
ABSTRACT Aim To develop a self‐paced digital learning tool incorporating newer learning strategies for dental students to supplement existing undergraduate teaching in dental traumatology (DT). The secondary aim was to pilot the learning tool to evaluate learner experience and changes in immediate knowledge scores.
Anne C. O'Connell, Rona Leith, Isabel C. Olegário   +2 more
wiley   +1 more source