Results 71 to 80 of about 6,227 (189)

Radiographic assessment of agenesis of the third molars: A cross-sectional study

Dentistry and Medical Research, 2023
Congenital absence of a tooth is known as dental agenesis or agenesis of a tooth. Although both deciduous and permanent dentition are prone to agenesis, permanent third molars are the most commonly affected teeth.
Nithiyasri Ganesan, T Maheswaran, Ganapathy Nalliyapan, Ilayaraja Vadivel, Dineshshankar Janardhanam, Yoithap Prabhunath Thuckanaickenpalayam Ragunathan   +5 more
doaj   +1 more source

Vitamin‐Responsive Disorders: From Molecular Basis to Clinical Presentation and Therapy

Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT Vitamin‐dependent cofactors are essential for numerous metabolic reactions, and defects affecting their uptake, conversion, utilisation, or regeneration constitute a heterogeneous group of inherited metabolic disorders (IMDs). Although dietary vitamin intake is sufficient to sustain coenzyme synthesis in healthy individuals, it is insufficient
Cécile Acquaviva, Yann Nadjar, Manuel Schiff, Christine Vianey‐Saban, Alain Fouilhoux, Jean‐François Benoist   +5 more
wiley   +1 more source

Molecular Basis and Clinical Spectrum of WNT10A‐Related Oligodontia

Clinical Genetics, Volume 110, Issue 1, Page 3-14, July 2026.
Cellular Mechanism behind WNT10A phenotypes. ABSTRACT WNT10A mutations, a major genetic determinant of dental agenesis and ectodermal dysplasia, exert profound effects on craniofacial development. Although classified as rare disorders, these mutations account for more than half of oligodontia cases, reflecting their critical role.
Perennes Elise, Benkirane‐Jessel Nadia, Anton Nicolas, Vandamme Thierry, Clauss François, Conzatti Guillaume   +5 more
wiley   +1 more source

Retinoic Acid Informs the Positional Identity of Frontonasal Neural Crest Cells Through Alx Family of Transcription Factors

The FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Retinoic acid (RA) regulates the positional identity of cranial neural crest cells (CNCCs) through the transcription factors Alx1 and Alx4. Upon receiving RA from the local environment, liganded RAR/RXR heterodimers activate the expression of Alx1 and Alx4, which promote the frontonasal identity of CNCCs and inhibit the first pharyngeal arch identity ...
Shuxuan Wu, Yifan Lu, Yixin Tu, Yuke Xi, Qianxue Wan, Minghui Yue, Huan Liu, Zhaoming Wu   +7 more
wiley   +1 more source

The phenotype and genotype of PAX9 mutations causing tooth agenesis

, 2023
Objectives: The purpose of this study was to identify associations between PAX9 mutations and clinical features of non-syndromic tooth agenesis patients.
Feng Wang, Yu, Kang, Shen, Yihan, Dai, Qinggang, Yihan Shen, Jiang, Cailing, Wu, Yiqun, Yiqun Wu, Cailing Jiang, Kang Yu, Qinggang Dai, Wang, Feng   +11 more
core   +1 more source

Two‐Year Follow‐Up of Ectodermal Dysplasia‐Syndactyly Syndrome 1 in a Palestinian Child Successfully Treated With Topical Minoxidil and Tretinoin: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
Clinical timeline of the reported EDSS1 case, illustrating disease onset, diagnostic milestones, treatment initiation, treatment modifications, and longitudinal response to combined topical minoxidil and tretinoin therapy from infancy through the last follow‐up.
Bana O. Aburajab, Hamza M. A. Ghaith, Nada Ishti, Muawia O. Aburajab   +3 more
wiley   +1 more source

A Comprehensive Review of the Genetic Etiology and Management of Orofacial Clefts

Pediatric Discovery, Volume 4, Issue 2, June 2026.
ABSTRACT Cleft lip (CL) and cleft palate (CP), collectively referred to as orofacial clefts (OFCs), are among the most common birth defects and can have significant effects on speech, nutrition, and physical and psychosocial development. Manifestation, classification, and treatment plans of OFCs are diverse and not standardized.
Emily Kim, Rebeka Dejenie, Caroline Kim, Russell Reid   +3 more
wiley   +1 more source

Tooth Agenesis

, 2012
Tooth agenesis denotes a condition where teeth are missing due to a developmental failure. According to severity, this malformation can be subdivided into hypodontia, oligodontia and anodontia.
Hans Ulrich Luder, Luder, Hans Ulrich, Thimios A Mitsiadis, Mitsiadis, Thimios A   +3 more
core   +1 more source

Colorectal cancer and self-reported tooth agenesis [PDF]

Hereditary Cancer in Clinical Practice, 2014
Germline mutations in APC and AXIN2 are both associated with colon neoplasia as well as anomalous dental development. We tested the hypothesis that congenitally missing teeth may occur more commonly in individuals diagnosed with colorectal cancer than in individuals without this diagnosis.Via a survey conducted on 1636 individuals with colorectal ...
Lindor, Noralane M, Win, Aung Ko, Gallinger, Steven, Daftary, Darshana, Thibodeau, Stephen N, Silva, Renato, Letra, Ariadne   +6 more
openaire   +3 more sources

Homo luzonensis and the role of homoplasy in the morphology of hominin insular species

Cladistics, Volume 42, Issue 3, Page 286-316, June 2026.
Abstract Homo luzonensis lived during the upper Pleistocene in the northern Philippines, east of the Wallace line. The few specimens attributed to this species show a mosaic of plesiomorphies for the genus Homo and apomorphies found in upper Pleistocene Homo species.
Pierre Gousset, Jérémie Bardin, Isabelle Rouget, Armand S. Mijares, Florent Détroit   +4 more
wiley   +1 more source