Results 91 to 100 of about 11,053 (253)

Molar incisor hypomineralisation: current knowledge and practice

International Dental Journal, EarlyView., 2020
Background Molar incisor hypomineralisation (MIH) is a common developmental dental condition that presents in childhood. Areas of poorly formed enamel affect one or more first permanent molars and can cause opacities on the anterior teeth. MIH presents a variety of challenges for the dental team as well as functional and social impacts for affected ...
Helen D. Rodd, Anna Graham, Niecoo Tajmehr, Laura Timms, Noren Hasmun   +4 more
wiley   +1 more source

Collagen Type VI Alpha 1 as a Regulator of Redox Homeostasis in Antioxidant‐Enhanced Osteogenesis of Dental Stem Cells

Cell Proliferation, EarlyView.
Under physiological conditions, NAC activates the PI3K‐AKT‐COL6A1 axis to sustain redox balance and enhance osteogenesis. COL6A1 deficiency, however, compromises this axis, inducing oxidative stress and impairing NAC's osteogenic efficacy. ABSTRACT Alveolar bone injury represents a prevalent clinical challenge in dentistry, for which stem cell‐based ...
Zhaosong Meng, Jiacheng Liu, Yue Zhang, Ruimeng Yang, Jingyi Zhang, Haosun Yang, Zheng Wang, Ran Wei, Zhe Li, Shuling Guo, Lizhi Hu, Lei Sui   +11 more
wiley   +1 more source

Chromatin Remodeller BRD9 Orchestrates Odontoblastic Differentiation via Coordinating RUNX2‐KLF4

Cell Proliferation, EarlyView.
During odontoblast lineage commitment, the chromatin remodeller BRD9 acts as a critical epigenetic coordinator, orchestrating the chromatin landscape to facilitate synergistic binding of key transcription factors RUNX2 and KLF4 to target loci for odontogenesis.
Wenrui Zeng, Yuxiu Lin, Yongyan Gao, Delan Huang, Yuanyuan Li, Honglei Ruan, Guohua Yuan, Huan Liu, Zhi Chen   +8 more
wiley   +1 more source

Genetic testing in paediatric neurological disorders

Developmental Medicine &Child Neurology, EarlyView.
In this study 390 paediatric patients with neurological disorders underwent genetic testing via exome sequencing, commercial panel, in‐house epilepsy, and movement disorder gene panels. Exome sequencing provides the highest diagnostic yield, and severe developmental delay and hypotonia predicted pathogenic variants in the exome sequencing cohort ...
Wafa Bani Uraba, Byoung Chan Lee, Shekeeb S. Mohammad, Katrina Fisk, Michael Buckley, Russell C. Dale, Tony Roscioli, Paediatric Neurogenomic Working Group, Manoj P. Menezes, Sachin Gupta, Christopher Troedson, Esther Tantsis, Richard Webster, Bruce Bennetts, Deepak Gill, Kavitha Kothur   +15 more
wiley   +1 more source

Adhesion of Newly Developed Composite Resin Splinting Materials to Enamel: Effect of Enamel Surface Treatment

Dental Traumatology, EarlyView.
ABSTRACT Background/Aim To evaluate the shear bond strength (SBS) of newly developed composite resin materials intended for dental splinting to enamel and to determine whether phosphoric acid etching alone provides reliable adhesion. Material and Methods Four experimental materials (G‐Fix, Light Fix, Ortho Connect, and Ortho Connect Flow) were compared
Wonkyu Shin, Ji‐Soo Song, Hyuntae Kim, Wonjoon Moon, Teo Jeon Shin, Shin Hye Chung, Jin‐Soo Ahn, Hong‐Keun Hyun   +7 more
wiley   +1 more source

Dens Invaginatus as a Biomechanical Risk Modifier in Dental Trauma: Finite Element Analysis

Dental Traumatology, EarlyView.
ABSTRACT Introduction/Aims Traumatic dental injuries are common in childhood and may adversely affect functional and psychosocial well‐being. Dens invaginatus, a developmental anomaly caused by the infolding of the enamel organ during odontogenesis, alters tooth morphology and may influence biomechanical behavior under traumatic loading.
Emine Şuranur Ayaz, Sema Aydınoğlu, Dilara Nil Günaçar, Ayberk Dizdar, Ecren Uzun Yaylaci, Murat Yaylaci, Mukaddes Yerebakan   +6 more
wiley   +1 more source

Revitalization in Traumatized Immature Teeth With External Inflammatory Root Resorption: A Systematic Review

Dental Traumatology, EarlyView.
ABSTRACT Introduction This study aimed to evaluate whether revitalization can be indicated in the treatment of traumatized immature teeth with external inflammatory root resorption (EIRR). Methods The protocol of the review was developed in accordance with the PRISMA checklist and registered in the PROSPERO database (CRD42023446609).
Ghina Al Khourdaji, Timothy Fasham, Samantha Elbhar, Kerstin M. Galler, Tchilalo Boukpessi   +4 more
wiley   +1 more source

Prevalence and Patterns of Multiple Injuries Affecting a Single Permanent Tooth (Combination Injuries): A Systematic Review and Meta‐Analysis

Dental Traumatology, EarlyView.
ABSTRACT Background Combination injuries or multiple traumatic dental injuries (TDI) affecting a single permanent tooth are clinically significant but remain underrecognized. Although the global prevalence of TDI is well documented, the epidemiology of combination injuries has not been clearly established. This systematic review and meta‐analysis aimed
Nitesh Tewari, Alina Wikstrom, Eva Lauridsen, Vijay Prakash Mathur, Partha Haldar, Lars Andersson, Georgios Tsilingaridis   +6 more
wiley   +1 more source

Prognosis of Traumatized Permanent Teeth Affected by Multiple Injuries (Combination Injuries): A Systematic Review and Meta‐Analysis

Dental Traumatology, EarlyView.
ABSTRACT Background/Aims The prognosis of traumatic dental injuries (TDI) of permanent teeth depends on several factors related to the injury, patient characteristics, management, and follow‐up protocols. When such injuries affect both hard dental tissues and the periodontium (“combination injuries”), the risk of adverse healing complications increases.
Nitesh Tewari, Alina Wikstrom, Eva Lauridsen, Vijay Prakash Mathur, Partha Haldar, Lars Andersson, Georgios Tsilingaridis   +6 more
wiley   +1 more source

Descriptive Evaluation of Medium‐ and Long‐Term Complications of Traumatic Dental Injuries in Children and Adolescents Reporting to a Tertiary Care Hospital

Dental Traumatology, EarlyView.
ABSTRACT Background/Aims Traumatic dental injuries (TDIs) frequently present with acute symptoms, yet many adverse outcomes manifest months or years later as medium‐ and long‐term consequences. These sequelae, such as pulp necrosis with infection of root canal system, periapical radiolucency, and external inflammatory resorption, pose significant ...
Shailja Srivastava, Nitesh Tewari, Vijay Prakash Mathur, Morankar Rahul, Kalpana Bansal, Georgios Tsilingaridis   +5 more
wiley   +1 more source