Machine learning‐assisted prediction of clinical responses to periodontal treatment
Abstract Background Periodontitis is among the most prevalent chronic inflammatory conditions globally, and is associated with bone resorption, tooth loss, and systemic complications. While its treatment is largely standardized, individual outcomes vary, with some patients experiencing further disease progression despite adherence. Methods We developed
Balazs Feher+5 more
wiley +1 more source
Peri‐implant inflammation increases the risk of osteonecrosis in mice treated with bisphosphonate
Abstract Background Bisphosphonates (BPs) are effective in managing bone diseases due to their anti‐resorptive properties but are linked to medication‐related osteonecrosis of the jaw (MRONJ), particularly concerning dental implants. This study explored the combined impact of ligature‐induced peri‐implant inflammation and zoledronic acid (ZA), a BP ...
Ana Bujila+11 more
wiley +1 more source
Whole genome sequencing increases the diagnostic rate in Charcot-Marie-Tooth disease. [PDF]
Record CJ+13 more
europepmc +1 more source
Transcriptome analysis of granulation tissue from periodontal osseous defects
Abstract Background Granulation tissue is routinely discarded in periodontal surgical procedures, but few studies have characterized it. The present study aimed to compare global gene expression in granulation tissue derived from different types of periodontal osseous defects.
Ye Han Sam+5 more
wiley +1 more source
Co-occurrence of Charcot-Marie-Tooth disease type 1 and glomerulosclerosis in a patient with a de novo INF2 variant. [PDF]
Ding Y, Wu Z, Tang X, Li X.
europepmc +1 more source
Abstract Background The exponential increase in dental implant use has led to a parallel rise in peri‐implant diseases (PID), adversely affecting implant therapy success and patient quality of life. Efforts have been made by the dental community to understand systemic, behavioral, and site‐level risk factors involved in the etiologies and pathogenesis ...
Hom‐Lay Wang+59 more
wiley +1 more source
ITPR3-associated neuropathy: Report of a further family with adult onset intermediate Charcot-Marie-Tooth disease. [PDF]
Cabello-Murgui J+8 more
europepmc +1 more source
Abstract We present a case of a young female patient with persistent and severe fat‐soluble vitamin deficiency since infancy. Despite extensive investigations during childhood, the underlying cause remained elusive. The patient was generally asymptomatic while receiving continuous vitamin subsidy.
Christine Rungoe+4 more
wiley +1 more source
Transfer RNA supplementation rescues HARS deficiency in a humanized yeast model of Charcot-Marie-Tooth disease. [PDF]
Wilhelm SDP+6 more
europepmc +1 more source
Recent Advances in Injectable Hydrogel Biotherapeutics for Regenerative Dental Medicine
This review analyses multifunctional injectable hydrogels, natural or synthetic, physically or chemically crosslinked, that deliver exosomes, stem cells, and other bioactive cues to inflamed or damaged oral tissues. We discuss their immunomodulatory, antimicrobial, angiogenic, and osteogenic capacities, highlighting advances that enable regenerative ...
Renan Dal‐Fabbro+6 more
wiley +1 more source