Results 31 to 40 of about 9,361,467 (352)

Charcot-Marie-Tooth disease and related disorders: an evolving landscape.

Current Opinion in Neurology, 2019
PURPOSE OF REVIEW Charcot-Marie-Tooth (CMT) disease and related disorders are the commonest group of inherited neuromuscular diseases and represent a heterogeneous group of disorders.
M. Laurá, M. Pipis, A. Rossor, M. Reilly   +3 more
semanticscholar   +1 more source

Mutation spectrum of Charcot‐Marie‐Tooth disease among the Han Chinese in Taiwan

Annals of Clinical and Translational Neurology, 2019
Charcot‐Marie‐Tooth disease (CMT) is a clinically and genetically heterogeneous group of inherited neuropathies. Mutations in more than 90 genes have been implicated in CMT; however, the mutational spectrum of CMT in Chinese population remains obscure ...
Yun‐Hsin Hsu, Kon-Ping Lin, Yuh-Cherng Guo, Yu-Shuen Tsai, Y. Liao, Yi-Chung Lee   +5 more
semanticscholar   +1 more source

Dental pulp stem cells accelerate wound healing through CCL2-induced M2 macrophages polarization

iScience, 2023
Summary: The crosstalk between mesenchymal stem cells (MSCs) and the host immune function plays a key role in the efficiency of tissue regeneration and wound healing.
Zi Yang, Linsha Ma, Conglin Du, Jingsong Wang, Chunmei Zhang, Lei Hu, Songlin Wang   +6 more
doaj  

Generation of functional oligopeptides that promote osteogenesis based on unsupervised deep learning of protein IDRs

Bone Research, 2022
Deep learning (DL) is currently revolutionizing peptide drug development due to both computational advances and the substantial recent expansion of digitized biological data. However, progress in oligopeptide drug development has been limited, likely due
Mingxiang Cai, Baichuan Xiao, Fujun Jin, Xiaopeng Xu, Yuwei Hua, Junhui Li, Pingping Niu, Meijing Liu, Jiaqi Wu, Rui Yue, Yong Zhang, Zuolin Wang, Yongbiao Zhang, Xiaogang Wang, Yao Sun   +14 more
doaj   +1 more source

Mutations in the MORC2 gene cause axonal Charcot-Marie-Tooth disease.

Brain : a journal of neurology, 2016
Charcot-Marie-Tooth disease (CMT) is a complex disorder with wide genetic heterogeneity. Here we present a new axonal Charcot-Marie-Tooth disease form, associated with the gene microrchidia family CW-type zinc finger 2 (MORC2).
T. Sevilla, V. Lupo, D. Martínez-Rubio, Paula Sancho, Rafael Sivera, M. J. Chumillas, M. García-Romero, S. Pascual-Pascual, N. Muelas, J. Dopazo, J. Vílchez, F. Palau, C. Espinós   +12 more
semanticscholar   +1 more source

The effect of mobile personalised texting versus non-personalised texting on the caries risk of underprivileged adults: a randomised control trial

BMC Oral Health, 2019
Background In the Republic of Ireland (RoI), fluoridation has been effective and efficient for caries prevention at population level, regardless of income status; however, at individual level it still has limitations.
Makiko Nishi, Virginia Kelleher, Michael Cronin, Finbarr Allen   +3 more
doaj   +1 more source

Phenotypic Variability of Childhood Charcot-Marie-Tooth Disease.

JAMA Neurology, 2016
IMPORTANCE Disease severity of childhood Charcot-Marie-Tooth disease (CMT) has not been extensively characterized, either within or between types of CMT to date.
Kayla M. D. Cornett, M. Menezes, P. Bray, M. Halaki, R. Shy, S. Yum, T. Estilow, I. Moroni, M. Foscan, E. Pagliano, D. Pareyson, M. Laurá, T. Bhandari, F. Muntoni, M. Reilly, R. Finkel, J. Sowden, K. Eichinger, D. Herrmann, M. Shy, J. Burns   +20 more
semanticscholar   +1 more source

Vestibular impairment in Charcot–Marie–Tooth disease [PDF]

Journal of Neurology, 2020
To find out if Charcot-Marie-Tooth (CMT) patients, who have peripheral vestibular as well as peripheral somatosensory impairment, have worse postural balance than those who do not.We studied 32 patients with various CMT phenotypes and genotypes. Vestibular function was measured with the video head impulse test (vHIT) which tests vestibulo-ocular reflex
Gülden Akdal, Koray Koçoğlu, Tural Tanrıverdizade, Elçin Bora, Fikret Bademkıran, Ayşe Nur Yüceyar, Özgül Ekmekçi, İhsan Şükrü Şengün, Hatice Karasoy   +8 more
openaire   +8 more sources

CNS phenotype in X linked Charcot- Marie-Tooth disease

Journal of Neurology Neurosurgery & Psychiatry, 2018
We read with interest the study by Koutsis et al reporting an increased prevalence of multiple sclerosis (MS) in their cohort of patients with X linked Charcot-Marie-Tooth disease (CMTX1).1 CMTX1 is a neurological condition with significant disability ...
Vinojini Vivekanandam, C. Hoskote, A. Rossor, M. Reilly   +3 more
semanticscholar   +1 more source

Myeloid-derived growth factor promotes M2 macrophage polarization and attenuates Sjögren’s syndrome via suppression of the CX3CL1/CX3CR1 axis

Frontiers in Immunology
IntroductionPrimary Sjögren syndrome (pSS) is a systemic autoimmune disease that is characterized by the infiltration of immune cells into the salivary glands.
Zi Yang, Zi Yang, Mangnan Liu, Zhichao Chang, Conglin Du, Yang Yang, Yang Yang, Chen Zhang, Liang Hu, Liang Hu   +9 more
doaj   +1 more source