Results 61 to 70 of about 9,361,467 (352)

M2 Macrophage‐Derived Extracellular Vesicles Reprogram Immature Neutrophils into Anxa1hi Neutrophils to Enhance Inflamed Bone Regeneration

Advanced Science, EarlyView.
This study reveals that M2‐EVs mitigate periodontitis‐induced bone resorption by modulating neutrophil fate. Single‐cell RNA sequencing identified an Anxa1hi neutrophil subpopulation with pro‐reparative properties. M2‐EVs disrupt neutrophil maturation, promoting this subpopulation through key reprogramming genes (Acvrl1, Fpr2). These findings highlight
Yufei Yao, Yijia Yin, Fangyuan Shuai, Waishan Lam, Tao Zhou, Yaxin Xie, Xuesong He, Xianglong Han   +7 more
wiley   +1 more source

Number of tooth loss in smokers and non-smokers in Monmata Lhoong Village, Aceh Besar District, Indonesia

Padjadjaran Journal of Dentistry, 2019
Introduction: Tooth loss is a condition that occurs in most of the world's population. The most common causes of tooth loss are caries and periodontal disease.
Liana Rahmayani, Dewi Saputri, Chairunas Chairunas, Syahrial Syahrial, Maisura Maisura   +4 more
doaj   +1 more source

CHCHD10 variant p.(Gly66Val) causes axonal Charcot-Marie-Tooth disease

Neurology: Genetics, 2015
Objective: We describe the phenotype consistent with axonal Charcot-Marie-Tooth disease type 2 (CMT2) in 4 families with a c.197G>T (p.(Gly66Val)) variant in CHCHD10. Methods: We sequenced the CHCHD10 gene in a cohort of 107 families with CMT2 of unknown
M. Auranen, E. Ylikallio, Maria Shcherbii, A. Paetau, S. Kiuru-Enari, J. Toppila, H. Tyynismaa   +6 more
semanticscholar   +1 more source

A MXene‐Based Nanothermal Knife Inhibits Aggresome‐Mediated Persister Formation for Preventing Dental Caries

Advanced Science, EarlyView.
Early childhood caries (ECC) involves cariogenic persisters that evade antimicrobial treatment. Persisters achieve this by downregulating heat shock proteins (HSPs) and formation of protein aggregates. Ti3C2 MXene‐based photothermal therapy (PTT) acts as a “nanothermal knife,” disrupting membranes, upregulating HSPs, inhibits aggregates, prevents ...
Yinyin Zhang, Leilei Yang, Jing jiao, Wenshuai Li, Sen Lin, Xianlong Zong, Haoyang Qin, Danfeng Liu, Rui Li   +8 more
wiley   +1 more source

ALS5/SPG11/ KIAA1840 mutations cause autosomal recessive axonal Charcot–Marie–Tooth disease

Brain : a journal of neurology, 2015
Mutations in the ALS5/SPG11/ KIAA1840 gene cause autosomal recessive hereditary spastic paraplegia or autosomal recessive juvenile amyotrophic lateral sclerosis. Montecchiani et al .
C. Montecchiani, L. Pedace, Temistocle Lo Giudice, Antonella Casella, Marzia Mearini, F. Gaudiello, J. Pedroso, C. Terracciano, C. Caltagirone, R. Massa, P. S. St George-Hyslop, O. Barsottini, T. Kawarai, A. Orlacchio   +13 more
semanticscholar   +1 more source

In Situ Valence Engineering of Copper Silicate Nanozymes with Enhanced Peroxidase‐Like Catalytic Activity for Oral Disease Detection

Advanced Science, EarlyView.
A novel copper silicate nanozyme (CSHSs‐Ar) with high peroxidase‐like catalytic activity and great catalytic specificity is well developed using a facile in situ valence‐engineered approach. The well‐developed CSHSs‐Ar nanozyme‐involved system can be utilized and employed as an efficient colorimetric sensor for the detection of volatile sulfur ...
Xiaocan Liu, Zhen Ding, Chengjing Xu, Jinming Zhang, Yufu Liu, Tianyan Chen, Shuang Dai, Xingfu Bao, Min Hu, Zhen Liu   +9 more
wiley   +1 more source

Polystyrene substrate effects on human dental pulp cell behavior: implications for in vitro culture optimization

BMC Oral Health
Objective This study aimed to test the hypothesis that human dental pulp cells (hDPCs) exhibited differential responses to non-tissue culture treated polystyrene (Non-TCPS) and TCPS in the context of odontogenic differentiation and mineralization ...
Jia Tang, Youjing Qiu
doaj   +1 more source

Saliva Microbiome Changes in Patients With Periodontitis With and Without Chronic Obstructive Pulmonary Disease

Frontiers in Cellular and Infection Microbiology, 2020
Objective: The oral microbiota plays a key part in the initial colonization by pathogens and the chronic inflammatory reaction of the host. We measured variations in the salivary microbiota and evaluated their potential associations with periodontitis ...
Mei Lin, Mei Lin, Xuefen Li, Jitian Wang, Cheng Cheng, Tianyi Zhang, Xiaozhe Han, Yiqing Song, Zuomin Wang, Songlin Wang, Songlin Wang   +10 more
doaj   +1 more source

An Off‐the‐Shelf Artificial Blood Clot Hydrogel Neutralizing Multiple Proinflammatory Mediators for Pro‐Regenerative Periodontitis Treatment

Advanced Science, EarlyView.
CCS‐RSF@PRP hydrogel is engineered to structurally and functionally mimic the blood clot by integrating PPR, CCS, and RSF nanofibers through in situ activation of PRP. In a rat periodontitis model, CCS‐RSF@PRP hydrogel effectively promotes periodontal tissue repair, attributing to neutralizing the multiple proinflammatory mediators, thus rebuilding a ...
Yini Huangfu, Zhezhe Zhao, Xiang Liu, Jingrong Wang, Yufeng Zhang, Tingting Lan, Yonglan Wang, Chenxuan Wu, Ju Zhang, Pingsheng Huang, Chuangnian Zhang, Anjie Dong, Zujian Feng, Deling Kong, Weiwei Wang   +14 more
wiley   +1 more source

Molecular Diagnosis of Charcot-Marie Tooth Disease

Pediatric Neurology Briefs, 2002
The frequency of mutations in certain genes in 153 unrelated patients with Charcot-Marie-Tooth disease (CMT) was determined by DNA sequencing before clinical testing at the Departments of Molecular and Human Genetics and Pediatrics, Baylor College of ...
J. Gordon Millichap
doaj   +1 more source