Results 151 to 160 of about 9,425,579 (399)
British Journal of Clinical Pharmacology, EarlyView.Abstract Aim To evaluate the safety, tolerability and pharmacokinetics in healthy participants of orally administered MMV367 (GSK3772701), a novel antimalarial interfering with Plasmodium falciparum acyl coenzyme A synthetase 10/11 function. Methods This first‐in‐human study enrolled 47 healthy male and female participants.
Andrea Kuemmerle +13 more
wiley +1 more source
Dental pathology detection in 3D cone-beam CT [PDF]
arXiv, 2018 Cone-beam computed tomography (CBCT) is a valuable imaging method in dental diagnostics that provides information not available in traditional 2D imaging. However, interpretation of CBCT images is a time-consuming process that requires a physician to work with complicated software.
arxiv
Frontiers in Dentistry, 2016 A case of multiple pulp stones, a supernumerary tooth and a congenitally missed tooth accompanied by several developmental dental anomalies concurrently affect- ing the upper and lower anterior teeth in an Iranian healthy girl is reported.
Maryam Ghasempour +3 more
doaj
Charcot-Marie-Tooth Disease and Respiratory Failure [PDF]
, 1987 Eric L. Dyer, Alfred Callahan
openalex +1 more source
Deciphering the skeletal interoceptive circuitry to control bone homeostasis
BMEMat, EarlyView.This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu +7 more
wiley +1 more source
Periodontal Bone Loss Analysis via Keypoint Detection With Heuristic Post-Processing [PDF]
arXivCalculating percentage bone loss is a critical test for periodontal disease staging but is sometimes imprecise and time consuming when manually calculated. This study evaluates the application of a deep learning keypoint and object detection model, YOLOv8-pose, for the automatic identification of localised periodontal bone loss landmarks, conditions ...
arxiv
Restoration of human tooth enamel
BMEMat, EarlyView.Human tooth enamel has remarkable properties but lacks self‐repair ability. Existing restorative materials cannot fully replicate enamel's microstructure and function, resulting in low restorative efficiency. This review summarizes the formation process and characteristics of enamel, and current restorative materials and future research directions are ...
Hanlin Liu +10 more
wiley +1 more source
Multiscale modelling couples patches of nonlinear wave-like simulations [PDF]
arXiv, 2014 The multiscale gap-tooth scheme is built from given microscale simulations of complicated physical processes to empower macroscale simulations. By coupling small patches of simulations over unsimulated physical gaps, large savings in computational time are possible.
arxiv
Dental plaque-inspired versatile nanosystem for caries prevention and tooth restoration
Bioactive Materials, 2023 Dental caries is one of the most prevalent human diseases resulting from tooth demineralization caused by acid production of bacteria plaque. It remains challenges for current practice to specifically identify, intervene and interrupt the development of ...
Yue Xu +9 more
doaj
Duplication within chromosome 17p11.2 in 12 families of French ancestry with Charcot-Marie-Tooth disease type 1a. The French CMT Research Group. [PDF]
, 1992 Alexis Brice +6 more
openalex +1 more source