Results 51 to 60 of about 2,430,968 (290)

The Impact of Weather on Emergency Visits for Acute Endodontic Treatment—A Retrospective Time-Series Study

Applied Sciences
Background: This study examines the correlation between extreme weather events and acute endodontic treatment-related emergency visits (AET-related EVs).
Marcus Rieder, Bernhard Remschmidt, Jan Gaessler, Markus Hribernig, Michael Payer, Norbert Jakse, Faris F. Brkic, David T. Liu   +7 more
doaj   +1 more source

The evolutionary paradox of tooth wear: simply destruction or inevitable adaptation? [PDF]

, 2013
Over the last century, humans from industrialized societies have witnessed a radical increase in some dental diseases. A severe problem concerns the loss of dental materials (enamel and dentine) at the buccal cervical region of the tooth.
Grosse, Ian R., Nguyen, Huynh Nhu, Huynh Nhu Nguyen, Ian R Grosse, Hublin, J. ; https://orcid.org/, Giorgio Gruppioni (406372), Schulz, Dieter, Nguyen, N., Kullmer, Ottmar, Giorgio Gruppioni, Stefano Benazzi (227062), Stefano Benazzi, Hublin, Jean-Jacques, Kullmer, O., Dieter Schulz (406371), Gruppioni, G., Jean-Jacques Hublin, Ian R. Grosse (356268), Ian R. Grosse, Jean-Jacques Hublin (406373), Dieter Schulz, Ottmar Kullmer (164077), Benazzi, S. ; https://orcid.org/, Schulz, D., Benazzi, Stefano, Huynh Nhu Nguyen (406370), Gruppioni, Giorgio, Grosse, I., Ottmar Kullmer, Jean Jacques Hublin   +29 more
core   +1 more source

An Efficient Detection Platform Based on Mesoporous Au@Cr2O3 Particles with Schwarz P Surface for Precise Periodontitis Metabolite Profiling

Advanced Science, EarlyView.
A non‐invasive periodontitis diagnosis platform was developed using Au nanoparticles‐decorated mesoporous Cr2O3 (Au@mCr2O3) particles with Schwarz P surface as matrix for saliva metabolic fingerprinting (SMFs) analysis via MALDI‐MS. With the assistance of machine learning of SMFs, this platform enables efficient diagnosis and the screening of potential
Yue Sun, Yan Wang, Fangying Shi, Wenhe Xie, Yiding Zhang, Heyuhan Zhang, Chunhui Deng, Limin Wu, Meihua Chen, Yonghui Deng   +9 more
wiley   +1 more source

TRAF6 Lactylation in Glycolytic Macrophages Drives NF‐κB Signaling and M1 Polarization During Orthodontic Tooth Movement

Advanced Science, EarlyView.
Schematic diagram showing compressive stress triggers glycolytic reprogramming and lactate accumulation in macrophages. Lactate mediates TRAF6 lactylation at K171/K180 dual sites, which enhances its K63‐linked ubiquitination to activate the NF‑κB pathway and promote M1 polarization. This cascade drives orthodontic tooth movement (OTM) and alveolar bone
Xinyi He, Guodong Zhao, Yun Hu, Wenya Bai, Hao Tan, Shuai Yuan, Sihan Yang, Ye Zhu, Xiaohui Xu, Leilei Zheng   +9 more
wiley   +1 more source

Tooth loss among adults with and without presence of systemic diseases – Age and Gender matched case control study

Journal of Oral Biology and Craniofacial Research
Background: Systemic diseases contribute to tooth loss by affecting immunity, circulation, and bone health. While most studies focus on elderly, this study assesses tooth loss among adults with and without systemic diseases to support early care. Aim: To
Deshpande Vijaya Lakshmi, S. Jagadeeswara Rao, Dolar Doshi, Twinkle Tiwari, Lunavath Preethi   +4 more
doaj   +1 more source

Tooth number abnormality: from bench to bedside

International Journal of Oral Science, 2023
Tooth number abnormality is one of the most common dental developmental diseases, which includes both tooth agenesis and supernumerary teeth. Tooth development is regulated by numerous developmental signals, such as the well-known Wnt, BMP, FGF, Shh and ...
Han Zhang, Xuyan Gong, Xiaoqiao Xu, Xiaogang Wang, Yao Sun   +4 more
doaj   +1 more source

Mitochondrial disease mimicking Charcot-Marie Tooth disease [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 2007
Charcot–Marie tooth disease (CMT) is a heterogenous group of peripheral neuropathies caused by various genetic defects. Three cases of mitochondrial myopathy, neuropathy and gastrointestinal encephalopathy (MNGIE) which initially presented with a peripheral neuropathy resembling CMT are described here.
Needham, M., Duley, J. A., Hammond, S., Herkes, G. K., Hirano, M., Sue, C. M.   +5 more
openaire   +6 more sources

WDR72 Promotes Neuroblastoma Stemness and Progression by Sequestering TRIM31‐Mediated Degradation of CBX8

Advanced Science, EarlyView.
This study unveiled that METTL14 mediates m6A modification of WDR72 mRNA to stabilize and enhance WDR72 expression, which disrupts TRIM31‐mediated ubiquitination of CBX8 protein and retards its degradation, finally the elevated CBX8 contributes to tumor stemness.
Huijuan Zeng, Zijie Ye, Manna Zheng, Jing Pan, Tianbao Tan, Jiliang Yang, Jiahao Li, Zhang Zhao, Tianzhu Long, Liyu Zhang, Gautam Sethi, Tianyou Yang, Chao Hu, Yan Zou   +13 more
wiley   +1 more source

X-linked Charcot-Marie-Tooth Disease [PDF]

Journal of the Peripheral Nervous System, 2005
AbstractThe X‐linked form of Charcot‐Marie‐Tooth disease (CMT1X) is the second most common form of hereditary motor and sensory neuropathy. The clinical phenotype is characterized by progressive muscle atrophy and weakness, areflexia, and variable sensory abnormalities; central nervous system manifestations occur, too.
Scherer, Steven S., Kleopa, Kleopas A.
openaire   +2 more sources

Targeting the KCNC3‐Dependent Anterior Insular‐Lateral Orbitofrontal Cortex Glutamatergic Circuit Attenuates Post‐Traumatic Anxiety

Advanced Science, EarlyView.
Frontal lobe traumatic brain injury is associated with hyperactivity of an insular–orbitofrontal circuit in both patients and mice. By combination of integrating functional imaging, cell‐type–specific circuit manipulation, single‐cell transcriptomics, and whole‐cell recordings, this work identifies the downregulation of the potassium channel KCNC3 in ...
Meng‐Ge Li, Xiao‐Bo Qian, Hai‐Long Zhang, Di Li, Ling Ji, Xin‐Chun Xu, Jia‐Sheng Ding, Li‐Jun Yin, Li Zhang, Guang‐Yin Xu, Rong Gao   +10 more
wiley   +1 more source