Results 201 to 210 of about 244,243 (353)

First‐in‐human safety, tolerability, pharmacokinetics and pilot food‐effect study of the candidate antimalarial compound MMV367

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim To evaluate the safety, tolerability and pharmacokinetics in healthy participants of orally administered MMV367 (GSK3772701), a novel antimalarial interfering with Plasmodium falciparum acyl coenzyme A synthetase 10/11 function. Methods This first‐in‐human study enrolled 47 healthy male and female participants.
Andrea Kuemmerle   +13 more
wiley   +1 more source

Comparative evaluation of the postbleaching application of sodium ascorbate, alpha‐tocopherol, and quercetin on shear bond strength of composite resin to enamel

open access: yesClinical and Experimental Dental Research, Volume 8, Issue 6, Page 1598-1604, December 2022., 2022
Abstract Objective This study aimed to evaluate and compare the impacts of the postbleaching application of sodium ascorbate, alpha‐tocopherol, and quercetin on the shear bond strength (SBS) of composite resin. Material and Methods 60 extracted intact maxillary first premolars were collected and were randomly divided into five experimental groups as ...
Marzieh Moradian   +3 more
wiley   +1 more source

Visual representations of energy and chemical bonding in biology and chemistry textbooks: A case study of ATP hydrolysis

open access: yesBiochemistry and Molecular Biology Education, EarlyView.
Abstract Energy is a crosscutting concept in science, but college students often perceive a mismatch between how their biology and chemistry courses discuss the topic. The challenge of reconciling these disciplinary differences can promote faulty reasoning—for example, biology students often develop the incorrect idea that breaking bonds is exothermic ...
Mingyu Yang   +3 more
wiley   +1 more source

Thickness and yttria percentage influences the fracture resistance of laminate veneer zirconia restorations

open access: yesClinical and Experimental Dental Research, Volume 8, Issue 6, Page 1413-1420, December 2022., 2022
Abstract Objectives Mechanical properties are cardinal for the long‐term clinical success of laminate veneer restorations but the selection of new restorative materials should ideally be based on clinical evidence, therefore, in vitro testing of dental materials is a good alternative to evaluate their properties and understand their behavior so this ...
Ali Dhahee Malallah, Nadia H. Hasan
wiley   +1 more source

Bronchoscopic cryoextraction of an extracted tooth [PDF]

open access: yesQJM: An International Journal of Medicine, 2019
Chih-Yu Chen   +2 more
openaire   +3 more sources

Deciphering the skeletal interoceptive circuitry to control bone homeostasis

open access: yesBMEMat, EarlyView.
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu   +7 more
wiley   +1 more source

Comparison of the fracture resistance of the teeth prepared with ProTaper Universal, ProTaper Next, and ProTaper Gold rotary files

open access: yesClinical and Experimental Dental Research, Volume 8, Issue 6, Page 1421-1425, December 2022., 2022
Abstract Objectives Root canal preparation can lead to cracks on the roots by creating stresses on the root canal walls, which decreases the fracture resistance of the tooth. The present study compared the fracture resistance of the teeth prepared by the ProTaper Universal (PTU), ProTaper Next (PTN), and ProTaper Gold (PTG) rotary file systems ...
Amin Salem Milani   +4 more
wiley   +1 more source

歯槽骨骨密度を用いた薬剤関連顎骨壊死のリスク評価 [PDF]

open access: yes
大阪歯科大学Osaka Dental University博士(歯学)Objectives: Osteosclerosis and a high bone mineral density (BMD) have been proposed as risk factors for medication-related osteonecrosis of the jaw (MRONJ). In the present study, we measured the alveolar BMD (al-BMD) of
Hmada, Shoo   +2 more
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