Profiling and functional characterization of long noncoding RNAs during human tooth development [PDF]
The regulatory processes in developmental biology research are significantly influenced by long non-coding RNAs (lncRNAs). However, the dynamics of lncRNA expression during human tooth development remain poorly understood.
Xiuge Gu+13 more
doaj +2 more sources
Mandible-derived extracellular vesicles regulate early tooth development in miniature swine via targeting KDM2B [PDF]
Tissue interactions play a crucial role in tooth development. Notably, extracellular vesicle-mediated interactions between the mandible and tooth germ are considered essential.
Ye Li, Meng Sun, Yi Ding, Ang Li
doaj +2 more sources
Morphometric approach to pulp fibroblast development in tooth germ. [PDF]
This paper builds a morphometric framework for the analysis of dental pulp fibroblast evolution during tooth development. We investigated 15 tooth germs (cases) organized, by histological criteria, in three groups corresponding to cap, early bell, and late bell stages, respectively. Each group comprised five cases. The morphometric description used the
Căruntu ID, Săvinescu SD, Amălinei C.
europepmc +4 more sources
Membrana preformativa: Unveiling the unexplored facets of dental development [PDF]
Aim: Odontogenesis is a complex and highly regulated biological process that involves a range of molecular mechanisms. Among these, Ki67 and Cyclin D1 are crucial cell cycle regulators that play pivotal roles in controlling cell proliferation during ...
Sakshi Sikaria+3 more
doaj +2 more sources
Isotretinoin: action on mice tooth germs and palate
Vitamin A and its derivates, acid retinoic, tretinoin and isotretinoin, are currently used in dermatological treatments. The administration of high doses of this vitamin provokes malformation in the following systems: central nervous, cardiovascular ...
Eleny Balducci Roslindo+3 more
doaj +3 more sources
Case Report: Digitally driven tooth autotransplantation using surgical templates and three-dimensional printed donor tooth replica [PDF]
Tooth autotransplantation is a procedure involving the surgical repositioning of a tooth or dental germ from one site in the mouth to another within the same individual. A successful procedure requires a donor tooth with healthy cementum and periodontium,
Iuliana Babiuc+5 more
doaj +2 more sources
Treatment of a Dentigerous Cyst with Transposition of the Permanent Tooth Germ: A Case Report [PDF]
Background: General factors such as endocrine disorders, osteopetrosis, Gorlin syndrome, and cleidocranial dysplasia or local factors such as supernumerary teeth, odontoma, cysts, tumors, dense mucoperiosteum, ankylosis, abnormal inclination and crowding,
Başak Kiziltan Eliaçik+2 more
doaj +1 more source
mTORC1 signaling pathway regulates tooth repair
Tooth germ injury can lead to abnormal tooth development and even tooth loss, affecting various aspects of the stomatognathic system including form, function, and appearance.
Honghong Liu+9 more
doaj +1 more source
Prevention of the disrupted enamel phenotype in Slc4a4-null mice using explant organ culture maintained in a living host kidney capsule. [PDF]
Slc4a4-null mice are a model of proximal renal tubular acidosis (pRTA). Slc4a4 encodes the electrogenic sodium base transporter NBCe1 that is involved in transcellular base transport and pH regulation during amelogenesis.
Kurtz, Ira, Paine, Michael L, Wen, Xin
core +12 more sources
Recent advances in regenerative technology have made the regeneration of various organs using pluripotent stem cells possible. However, a simpler screening method for evaluating regenerated organs is required to apply this technology to clinical ...
Tomomi Yuta+11 more
doaj +1 more source