Application of cryopreservation to tooth germ transplantation for root development and tooth eruption [PDF]
Scientific Reports, 2021 We cryopreserved mouse tooth germs with widely open cervical margins of the enamel organ to overcome difficulties in cryoprotectant permeation and tested their efficacy by transplanting them into recipient mice. The upper right first molar germs of 8-day-
Xinghan Li +3 more
doaj +6 more sources
TOOTH GERM CYSTS OF THE JAW [PDF]
Annals of Surgery, 1916 n ...
Michael G. Wohl
semanticscholar +6 more sources
BMP9-initiated osteogenic/odontogenic differentiation of mouse tooth germ mesenchymal cells (TGMCS) requires Wnt/β-catenin signalling activity. [PDF]
J Cell Mol Med, 2021 Teeth arise from the tooth germ through sequential and reciprocal interactions between immature epithelium and mesenchyme during development. However, the detailed mechanism underlying tooth development from tooth germ mesenchymal cells (TGMCs) remains ...
Luo W +20 more
europepmc +2 more sources
Wnt/β-catenin signaling, which is activated in odontomas, reduces Sema3A expression to regulate odontogenic epithelial cell proliferation and tooth germ development. [PDF]
Sci Rep, 2019 Odontomas, developmental anomalies of tooth germ, frequently occur in familial adenomatous polyposis patients with activated Wnt/β-catenin signaling. However, roles of Wnt/β-catenin signaling in odontomas or odontogenic cells are unclear.
Fujii S +7 more
europepmc +2 more sources
Practical whole-tooth restoration utilizing autologous bioengineered tooth germ transplantation in a postnatal canine model. [PDF]
Sci Rep, 2017 Whole-organ regeneration has great potential for the replacement of dysfunctional organs through the reconstruction of a fully functional bioengineered organ using three-dimensional cell manipulation in vitro.
Ono M +14 more
europepmc +2 more sources
Expression of p63 in tooth germ, dentigerous cyst and ameloblastoma.
J Oral Maxillofac Pathol, 2019 Context: To assess the role of p63, a p53 homolog, in the cytodifferentiation (odontogenesis) and oncogenesis of odontogenic epithelium. Aim: The present study aimed to compare the expression pattern of p63 in the epithelium of tooth germ, dentigerous ...
Gupta R +5 more
europepmc +2 more sources
Multiphoton microscopy imaging of developing tooth germs
Journal of the Formosan Medical Association, 2014 Traditionally, tooth germ is observed by histological investigation with hematoxylin and eosin stain and information may loss during the process. The purpose of this study is to use multiphoton laser fluorescence microscopy to observe the developing ...
Pei-Yu Pan +5 more
doaj +4 more sources
Genome-wide DNA methylation profile of developing deciduous tooth germ in miniature pigs. [PDF]
BMC Genomics, 2016 DNA methylation is an important epigenetic modification critical to the regulation of gene expression during development. To date, little is known about the role of DNA methylation in tooth development in large animal models.
Su Y +8 more
europepmc +2 more sources
Evaluation of the effect on the permanent tooth germ and the adjacent teeth by finite element impact analysis in the traumatized primary tooth [PDF]
International Journal of Paediatric DentistryBACKGROUND One of the primary concerns in the paediatric emergencies is traumatic dental injuries. OBJECTIVE This study aimed to create trauma in primary teeth and reveal its effects finite element analysis.
Ayça Kurt +6 more
openalex +2 more sources
Distribution of Cathepsin K in Late Stage of Tooth Germ Development and Its Function in Degrading Enamel Matrix Proteins in Mouse. [PDF]
PLoS One, 2017 Cathepsin K (CTSK) is a member of cysteine proteinase family, and is predominantly expressed in osteoclastsfor degradationof bone matrix proteins. Given the similarity in physical properties of bone and dental mineralized tissues, including enamel ...
Jiang T +6 more
europepmc +2 more sources