Results 51 to 60 of about 1,853,414 (290)

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source

Delayed tooth movement in Runx2+/− mice associated with mTORC2 in stretch-induced bone formation

Bone Reports, 2020
Runt-related transcription factor 2 (Runx2) is an essential transcription factor for osteoblast differentiation, and is activated by mechanical stress to promote osteoblast function.
Tomo Aonuma, Nagato Tamamura, Tomohiro Fukunaga, Yuichi Sakai, Nobuo Takeshita, Shohei Shigemi, Takashi Yamashiro, Irma Thesleff, Teruko Takano-Yamamoto   +8 more
doaj   +1 more source

Retrograde nerve growth factor signaling modulates tooth mechanical hyperalgesia induced by orthodontic tooth movement via acid-sensing ion channel 3

International Journal of Oral Science, 2021
Orthodontic tooth movement elicits alveolar bone remodeling and orofacial pain that is manifested by tooth mechanical hyperalgesia. Nerve growth factor (NGF) is upregulated in periodontium and may modulate tooth mechanical hyperalgesia.
Meiya Gao, Xinyu Yan, Yanzhu Lu, Linghuan Ren, Shizhen Zhang, Xiaoqi Zhang, Qianyun Kuang, Lu Liu, Jing Zhou, Yan Wang, Wenli Lai, Hu Long   +11 more
doaj   +1 more source

Leptin levels in gingival crevicular fluid during orthodontic tooth movement

Journal of Pharmacy and Bioallied Sciences, 2021
Aim: To evaluate the levels of leptin in gingival crevicular fluid (GCF) during orthodontic tooth movement and to find the role of leptin as a mediator for tooth movement. Materials and Methods: GCF was collected from 25 subjects and the levels of leptin
Joseph Alaguselvaraj, Kandanraj Selvaraj, Porselvi Bhaskaran, Sainath Muthiah Chidambaram, Thanigainathan Rajasekaran, Muralimani Mani   +5 more
doaj   +1 more source

The E3 Ubiquitin Ligase RLIM Safeguards Oligodendrocyte Development and Myelination by Targeting SLC7A11 for Polyubiquitination to Regulate Ferroptotic Resistance

Advanced Science, EarlyView.
RLIM‐mediated SLC7A11 polyubiquitination is required for SPTBN2‐mediated trafficking and membrane localization of SLC7A11, which enables oligodendrocyte precursor cells to be resistant to ferroptosis and safeguards oligodendrocyte lineage progression and thus myelination.
Yuwei Li, Haijun Zhang, Jieya Zhou, Shiyu Yang, Jingmei Cha, Gaofeng Yan, Shuhua Zhao, Bingyu Mao, Pengcheng Ma   +8 more
wiley   +1 more source

Micro-CT study of the influence of orthodontic force on the root resorption and orthodontic tooth movement

口腔疾病防治, 2016
Objective To analyze the tooth movement distance and root resorption in rats under different orthodontic forces, to explore the effect of orthodontic force on the root resorption during orthodontic tooth movement.Methods 64 male Sprague Dawley (SD) rats ...
WU Chang-jing
doaj   +1 more source

Digital model superimpositions: are different software algorithms equally accurate in quantifying linear tooth movements?

BMC Oral Health, 2022
Background To evaluate the accuracy of three different 3D digital model registration software packages for linear tooth movement measurements, with reference to a 3D digital virtual setup (DS).
Samar M. Adel, Nikhilesh R. Vaid, Nadia El-Harouni, Hassan Kassem, Abbas R. Zaher   +4 more
doaj   +1 more source

Effect of autophagy on aging-related changes in orthodontic tooth movement in rats

BMC Oral Health
Background The number of adult orthodontic patients is increasing, and studies have shown that autophagy is involved in regulating orthodontic tooth movement and plays an important role in aging-related changes. Therefore, we aimed to explore the role of
Bowen Xu, Chuhan Peng, Yugui Du, Qiuying Li, Kai Yang   +4 more
doaj   +1 more source

Knowledge on dental trauma and orthodontic tooth movement held by a group of orthodontists

Brazilian Oral Research, 2010
The objective of this work was to assess the knowledge about orthodontic tooth movement and dental trauma held by a group of orthodontists in specific areas of Brazil.
Pedro Marcelo Tondelli, Marcos Rogério de Mendonça, Osmar Aparecido Cuoghi, Alex Luiz Pozzobon Pereira, Mauro Carlos Agner Busato   +4 more
doaj   +1 more source

Accelerated orthodontic tooth movement: surgical techniques and the regional acceleratory phenomenon

Maxillofacial Plastic and Reconstructive Surgery, 2022
Background Techniques to accelerate tooth movement have been a topic of interest in orthodontics over the past decade. As orthodontic treatment time is linked to potential detrimental effects, such as increased decalcification, dental caries, root ...
Elif Keser, Farhad B. Naini
doaj   +1 more source