Results 41 to 50 of about 16,476 (258)

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source

Sensory Nerve‐Derived CGRP Controls Osteoclastogenesis by Limiting Macrophage Bioenergetics in Bone Repair

Advanced Science, EarlyView.
Sensory nerves help bones heal. This study shows that the neuropeptide CGRP, released from sensory nerves, slows down macrophage energy production, preventing excessive bone breakdown. By revealing this nerve–immune–metabolism connection, the work provides new insight into how the body balances bone repair and opens doors to targeted treatments ...
Jiaying Liu, Ting Zhang, Yuqing Mu, Lili Li, Ju Jin, Kevin J Dudley, Wendong Gao, Donglin Cai, Fuhua Yan, Lan Xiao, Yin Xiao   +10 more
wiley   +1 more source

Importance of Attachments in Treatment with Clear Aligners: A Narrative Review

Journal of Dental School, 2021
Objectives At present, clear aligners are widely used for treatment of complicated orthodontic cases such as severe crowding, and class II or III malocclusion.
Kazem Dalaie, Samin Ghaffari
doaj   +1 more source

Genetic Diagnosis and Discovery Enabled by Large Language Models

Advanced Science, EarlyView.
We demonstrate that large language models (LLMs) can facilitate genetic diagnosis and discovery. LLMs were used to solve four types of genetic problems of sequentially increased complexity. An LLM‐based pipeline could analyze genetic variants in the genomic sequences of human hearing loss or rare genetic disease patients and assist in identifying ...
Tao Tu, Khaled Saab, Weida Liu, Zhouqing Fang, Zhuanfen Cheng, Svetolik Spasic, Maja Djurisic, Hiroaki Mohri, Wenlong Ren, Anil Palepu, Juraj Gottweis, Alan Karthikesalingam, Kavita Kulkarni, Annalisa Pawlosky, Devon Bonner, Elijah Kravets, Shruti Marwaha, Hector R. Mendez, Matthew T. Wheeler, Jonathan A. Bernstein, Undiagnosed Diseases Network, Cheng‐Yu Tsai, Chen‐Chi Wu, Konstantina M. Stankovic, Vivek Natarajan, Gary Peltz   +25 more
wiley   +1 more source

Identification of a Force‐Induced Sox9+Acan+ Transitional Subpopulation Linked to FGF2–FGFR2–ERK Signaling in Orthodontic Bone Remodeling

Advanced Science, EarlyView.
Mechanical loading induces a previously unrecognized Sox9+Acan+ transitional mesenchymal cell population in the periodontal ligament that promotes osteoclastogenesis via the FGF2–FGFR2–ERK axis. Targeting this mechanoresponsive stromal population using a localized GelMA@siRNA delivery strategy attenuates pathological osteoclast overactivation and root ...
Miao Tan, Minyu He, Mingrui Zong, Qiya Tang, Yinan Liu, Jiaju Deng, Shun Huang, Xiaoxiao Lei, Jie Li, Lan Huang   +9 more
wiley   +1 more source

Linear Dimensional Change in Acrylic Denture Teeth Positions Factored by Different Processing Techniques and Occlusal Forms: An In Vitro Study

Applied Sciences, 2022
The current literature lacks substantial evidence for the effect of denture base processing techniques and posterior denture tooth forms on denture tooth shifts due to denture base resin polymerization.
Mohammed E. Sayed, Amit Porwal, Saurabh Jain, Abdulkarim Hussain Alshehri, Nasser M. Alqahtani, Ashwaq Hadi Ali Hadadi, Rawan Abdulwadoud Zakri, Sahar Mahdi Musa Zeed, Saswan Ibrahim Nahari, Fatimah H. Alsurayyie, Hatem Alqarni, Saeed M. Alqahtani, Saad Saleh AlResayes   +12 more
doaj   +1 more source

A Accelerating tooth movement with modified surgical and dentoalveolar distraction technique- a case report

Journal of Health Sciences, 2019
The duration of treatment is the most concern among orthodontic patients. It is of a challenge for an orthodontist to shorten the treatment time. A new surgical technique was introduced to accelerate tooth movement during orthodontic treatment. This new technique is the surgical reduction of bone mass in the pathway of desired tooth movement before ...
Wael Ahmed Bayomy Mohamed, Rozita Hassan, Shaifulizan Abdul Rahman   +2 more
openaire   +3 more sources

Development and Structural Characterization of UTE‐156, a Covalent Inhibitor of the VCP/p97 AAA+ ATPase

Advanced Science, EarlyView.
The AAA+ ATPase Valosin‐containing protein (VCP/p97) regulates protein homeostasis by unfolding ubiquitinated substrates. Here, we describe UTE‐156, a novel irreversible covalent inhibitor that modifies Cys522 in the D2 ATPase motor domain. Although its pharmacochemical limitations preclude immediate therapeutic use, UTE‐156 serves as a valuable ...
Daniela Tamayo‐Jaramillo, Subramanya Hegde, Xuan Jia, Kimberly Coffman, Hariprasad Vankayalapati, David Bearss, Kevin B. Jones, Alex W. Stark, Peter S. Shen   +8 more
wiley   +1 more source

Effect of Long-Term Captopril Administration on Bone Density and Orthodontic Tooth Movement

Journal of Islamic Dental Association of Iran, 2016
Background and Aim: Captopril is an oral angiotensin-converting-enzyme (ACE) inhibitor extensively used in the treatment of hypertension and heart failure.
Amir Hossein Mirhashemi, Mohammad Sadegh Ahmad Akhoundi, Elahe Ansari, Sedigheh Sheikhzadeh, Nafiseh Momeni, Ahmadreza Dehpour, Shahroo Etemad-Moghadam, Yasaman Kheirandish, Homa Farhadifard   +8 more
doaj  

Rethinking Power Solutions for Healthcare Wearables: From Point‐of‐Care and Episodic use to Continuous Monitoring and Therapeutic Platforms

Advanced Energy and Sustainability Research, EarlyView.
This Perspective examines practical power solutions for wearable healthcare systems, highlighting the limits of standard batteries. It categorizes wearables into four domains—point‐of‐care diagnostics, episodic monitoring, continuous long‐term monitoring, and therapeutic platforms—and analyzes their power needs.
Seokheun Choi
wiley   +1 more source