Results 101 to 110 of about 517,539 (201)

Myeloid A20 Regulates Periodontal Tissue Integrity and Temporomandibular Joint Structure

Journal of Periodontal Research, EarlyView.
Dysregulation of A20 signaling has been implicated in several immune‐mediated diseases, including rheumatoid arthritis and psoriasis, conditions characterized by excessive NF‐κB activation and inflammatory tissue damage. The structural alterations observed in this model suggest that impaired regulation of innate immune signaling may increase ...
Karol Alí Apaza Alccayhuaman, Patrick Heimel, Toni Dobsak, Stefan Tangl, Geert van Loo, Dieter D. Bosshardt, Reinhard Gruber   +6 more
wiley   +1 more source

Periodontitis and Inflammatory Bowel Diseases: Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This review aims to provide a conceptual framework for understanding the mechanistic interplay between periodontitis and IBD, with a particular emphasis on the microbial and immunological crosstalk linking the oral cavity and the gastrointestinal tract.
Ana Paula V. Colombo, Adriana M. de Oliveira, Nobuhiko Kamada, Sho Kitamoto   +3 more
wiley   +1 more source

Assessing the Impact of Treatment Duration and Demineralization on Enamel Fluoride Uptake

Acta Stomatologica Croatica
Objectives: This study aimed to determine the effect of time span between exposing the enamel to calcium lactate and sodium fluoride and of a demineralized surface on the uptake of alkali-soluble fluorides.
Fjolla Kullashi Spahija, Ivana Šutej, Krešimir Bašić, Kreshnik Spahija, Kristina Peroš   +4 more
doaj   +1 more source

Osteoporosis and Periodontitis: Two‐Way Epidemiological and Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This review investigates the main mechanistic pathways connecting local periodontitis to systemic osteoporosis. Seven interconnected mechanisms are identified. ABSTRACT Osteoporosis and periodontitis are highly prevalent, chronic inflammatory diseases that constitute a major global health burden.
Jia Chang, Geeta Madhuri Bhuvanagiri, Megan Dulkanchainun, Cunyu Wang   +3 more
wiley   +1 more source

Formulation Redesigning of Itaconate Treats Periodontitis via Nrf2/TFAM‐Mediated Reprogramming of Mitochondrial Metabolism

SmartMat
Periodontitis is the leading cause of tooth loss in adults. Unfortunately, inflammation remains poorly controlled and prone to relapse, even after removing the initial plaque biofilm.
Yanqun Liu, Baosheng Li, Jingyi Duan, Tianyang Han, Fengming Ye, Huan Xia, Yanzhen Ou, Xiaoyu Li, Qing Cai, Weiyan Meng, Shoujun Zhu   +10 more
doaj   +1 more source

Oral Neuroimmune Network and Mast Cells

European Journal of Inflammation, 2009
Inflammation is a critical process in the oral cavity, especially in gingival inflammation and pulpitis, as seen in periodontitis and decayed tooth structure. Nevertheless, the cellular process involved in oral inflammation is not well delineated. Recent
V. Karapanou, D. Kempuraj, T.C. Theoharides   +2 more
doaj   +1 more source

Oral Health, Periodontitis, and Respiratory Diseases: Biological Pathways

Journal of Periodontal Research, EarlyView.
This narrative review aims to provide a comprehensive update on the potential mechanisms by which poor oral health and periodontitis impact lung health, focusing on pneumonia, COPD, and asthma. ABSTRACT Poor oral hygiene and periodontitis influence lung diseases such as pneumonia, chronic obstructive pulmonary disease (COPD), COVID‐19, and asthma.
Raluca P. Vacaru, Andreea C. Didilescu, Frank A. Scannapieco   +2 more
wiley   +1 more source

Consequences of Tooth Loss on Oral Function and need for Replacement of Missing Teeth Among Patients Attending Muhimbili Dental Clinic [PDF]

, 2011
Tanzanian oral health services constitute mainly of tooth extractions. Consequently, individuals susceptible to dental caries and periodontal diseases will have a substantial number of missing teeth, which can affect oral function.
Quaker, Andrewleon S
core  

Periodontitis and Adverse Pregnancy Outcomes: Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This narrative review aims to describe mechanisms linking periodontal diseases in pregnancy with adverse pregnancy outcomes. ABSTRACT Periodontal diseases, including both gingivitis and periodontitis, occur commonly among pregnant individuals. Both gingivitis and periodontitis are associated with adverse pregnancy outcomes (APOs) such as early ...
Gregory C. Valentine, Yiorgos A. Bobetsis, Benjamin C. Shayo, Peter Milgrom, Phoebus N. Madianos   +4 more
wiley   +1 more source

The Oral‐Hepatic Axis: Epidemiological and Mechanistic Links Between Periodontal and Liver Diseases

Journal of Periodontal Research, EarlyView.
This review summarizes current epidemiological, clinical and mechanistic evidence linking periodontitis and chronic liver diseases, highlighting the oral‐gut‐liver axis, shared immunometabolic and nutritional pathways and opportunities for integrated preventive and therapeutic strategies.
Sinem Esra Sahingur, Kinga Grzech‐Leśniak, Samuel F. Suslavich, Janina Golob Deeb   +3 more
wiley   +1 more source