Results 131 to 140 of about 517,539 (201)

Metabolic reprogramming of the immune response in periodontitis

Periodontology 2000, EarlyView.
Abstract Objective Periodontitis, a highly prevalent chronic inflammatory disease, is characterized by the progressive destruction of the tooth‐supporting tissues, ultimately causing tooth loss. In recent years, the emerging field of immunometabolism has revealed that immune cell function is tightly regulated by intracellular metabolic pathways that ...
Rafael Scaf de Molon, Melissa Grant, Iain Chapple, Joao Paulo Steffens   +3 more
wiley   +1 more source

From mouth to brain: Linking periodontal and peri‐implant dysbiosis to systemic inflammation and neuropathology

Periodontology 2000, EarlyView.
Abstract Background/Aim Growing evidence suggests that imbalances occurring within the human microbiota and deregulation of the host immune response may play a significant role in the development of neurodegenerative diseases. Materials and Methods A comprehensive narrative review of the latest experimental, clinical, and epidemiological insights was ...
Emilio A. Cafferata, Frank Schwarz, Jaime Díaz‐Zúñiga, Alpdogan Kantarci   +3 more
wiley   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

Sustainable and Seismically Resilient Confined Masonry: Global Progress in Research and Design Practice

Earthquake Spectra, Volume 42, Issue 4, November 2026.
Modern confined masonry (CM) construction consists of masonry walls confined by reinforced concrete (RC) tie‐columns and tie‐beams. When built correctly, CM buildings have shown good performance in earthquake's shaking. Even though CM construction has been practised for almost a century in some Latin American countries, its use and standardisation are ...
Ahsana Parammal Vatteri, Svetlana Brzev, Dina D’Ayala, Sergio M. Alcocer, Sebastian Kaminski, Vaibhav Singhal, Aidarbek Stamov, Anna Pavan, Daniel Quiun, Dexter Lo, Erwin Lim, Hemant B. Kaushik, Juan José Pérez‐Gavilán, Julian Thamboo, Mahdi Eghbali, Marcos M. Chávez, Qaisar Ali, Ramesh Guragain, Sofia Andrade, Tim Hart, Ulugbek Begaliev, Yunita Idris, Radu Vacareanu, Daniar Abdykalykov   +23 more
wiley   +1 more source

Accessing Polyphenols Effect on Bond Strength and Dentin Enzymatic Degradation

Clinical and Experimental Dental Research, Volume 12, Issue 5, October 2026.
ABSTRACT Introduction Polyphenols have been investigated in dental materials and restorative techniques due to their interactions with metal cations, antioxidant activity, and collagen crosslinking ability, which make them a promise for reinforcing the dental substrate and improving material adhesion.
Ana Catarina Rios Castro Alves, Adonias Antonio da Silva, Roberta Bruno da Silva, Rayan de Lima França, Dayse Andrade Romão, de Fragoso, Natanael Barbosa dos Santos, de Porto   +7 more
wiley   +1 more source

Gastrointestinal Microbiome Dysbiosis in Cancer Development: Mechanisms and Biomarker Potential

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Dysbiosis of the gastrointestinal microbiome plays a role in carcinogenesis by inducing chronic inflammation, DNA damage, and activation of signaling pathways such as NF‐κB, STAT3, and Wnt/β‐catenin. Microorganisms such as Helicobacter pylori, Fusobacterium nucleatum, and Bacteroides fragilis promote the development of gastrointestinal tumors through ...
Negar Asgari, Mehrasa Asghari, Touraj Farazmandfar   +2 more
wiley   +1 more source

Single‐ or two‐visits endodontic treatment: Impact of irrigants on surface roughness, microhardness, topography, and fracture resistance of root dentin

European Journal of Oral Sciences, Volume 134, Issue 5, October 2026.
Abstract This study evaluated the effect of the number of simulated endodontic treatment visits and the type of irrigant on the surface roughness, microhardness, topography, and fracture resistance of root dentin. Bovine roots were distributed into six groups (n = 14) according to the irrigant and number of treatment visits: 0.9% saline solution ...
Yasmin Padoin, Sidnei Flores de Pellegrin, Duvan Cala Castillo, William Lemos Bevilaqua, Gabriel Kalil Rocha Pereira, Guilherme Pauletto   +5 more
wiley   +1 more source

Role of adjunctive methacryloyloxydecyl dihydrogen phosphate primers on dentin bond strength of universal adhesives under saliva and artificial aging

European Journal of Oral Sciences, Volume 134, Issue 5, October 2026.
Abstract This study evaluated whether adjunctive 10‐methacryloyloxydecyl dihydrogen phosphate (MDP) primers enhance the microtensile bond strength (µTBS) of two universal adhesives (UAs) to dentin under artificial aging and repeated salivary contamination applied at each bonding step.
Marjorie Zanini, Amélie Mainjot, Stéphane Le Goff, Jean‐François Nguyen   +3 more
wiley   +1 more source

Navigating Emergency Care After Injury: A Qualitative Study of Asylum Seekers and Refugees in England and Wales Using the Candidacy Framework (BE SURE Study)

Health Expectations, Volume 29, Issue 5, October 2026.
ABSTRACT Background Asylum seekers and refugees (ASRs) face significant challenges when accessing emergency and pre‐hospital care following injury. Language barriers, unfamiliarity with service pathways and limited trust in authorities hinder access to emergency services.
Ashrafunnesa Khanom, Lydia Jones, Hanifah M. Khanom, Fadi Baghdadi, Ann John, Alison Porter, Helen Snooks, Niroshan Siriwardena, Julia Williams, Thanuja Hettiarachchi, Solmaz Safari   +10 more
wiley   +1 more source

The Role of Neuropeptide Y in Dental Pulp: Balancing Neurogenic Inflammation and Pain Modulation

International Endodontic Journal, Volume 59, Issue 10, Page 2028-2045, October 2026.
ABSTRACT Background Dental pulp is a densely innervated, low‐compliance tissue in which neurogenic inflammation can rapidly escalate into oedema, raised intrapulpal pressure, microvascular compromise, and pain. While Substance P (SP) and Calcitonin gene‐related peptide (CGRP) are well‐established drivers of pulp vasodilation, the Neuroopeptide Y (NPY ...
Javier Caviedes‐Bucheli, Esteban Ulate, Hugo‐Roberto Munoz, Nestor Ríos‐Osorio   +3 more
wiley   +1 more source