Results 71 to 80 of about 517,539 (201)

Decision trees to characterise the roles of permeability and solubility on the prediction of oral absorption. [PDF]

open access: yes, 2015
Oral absorption depends on many physiological, physiochemical and formulation factors. Two important properties that govern oral absorption are in vitro permeability and solubility, which are commonly used as indicators of human intestinal absorption ...
Newby, Danielle   +6 more
core   +1 more source

High‐Fat Diet Reprograms the Periapical Immune Landscape in a Mouse Model of Apical Periodontitis: A Spatial Transcriptomics Study

open access: yesInternational Endodontic Journal, EarlyView.
ABSTRACT Introduction Apical periodontitis (AP) is an inflammatory disease of the periapical tissues driven by host responses to endodontic infection, and systemic metabolic disturbances, such as high‐fat diet (HFD)–induced dysmetabolism, may exacerbate tissue destruction. This study aimed to determine how chronic HFD exposure alters periapical myeloid
Maryam Ghaffari   +3 more
wiley   +1 more source

Investigation of torque characteristics in a novel permanent magnet flux switching machine with an outer-rotor configuration [PDF]

open access: yes, 2014
This paper comprehensively investigates the torque characteristics of a novel permanent magnet flux switching machine with outer-rotor configuration.
Miao, Dong-Min   +3 more
core   +1 more source

Claudin Loss-of-Function Disrupts Tight Junctions and Impairs Amelogenesis

open access: yesFrontiers in Physiology, 2017
Claudins are a family of proteins that forms paracellular barriers and pores determining tight junctions (TJ) permeability. Claudin-16 and -19 are pore forming TJ proteins allowing calcium and magnesium reabsorption in the thick ascending limb of Henle's
Claire Bardet   +11 more
doaj   +1 more source

Prevention and Management of Tooth Discolouration of Endodontic Origin (DEO): A State‐of‐the‐Art Review

open access: yesInternational Endodontic Journal, EarlyView.
ABSTRACT Background Tooth discolouration of endodontic origin (DEO) refers to an undesirable change in tooth colour arising from the pulp space as a result of reactive physiological processes, pathological processes or endodontic procedures and materials. As DEO frequently affects teeth in the aesthetic zone, it may substantially impair self‐esteem and
Gabriel Krastl   +7 more
wiley   +1 more source

Increased susceptibility of striatal mitochondria to calcium-induced permeability transition [PDF]

open access: yes, 2003
Mitochondria were simultaneously isolated from striatum and cortex of adult rats and compared in functional assays for their sensitivity to calcium activation of the permeability transition.
Brustovetsky, T   +11 more
core   +1 more source

Stress field evolution and crack extension law of coal breaking with flexible cutting tools

open access: yesMeitan xuebao
Flexible cutting tools reaming is a new method of coal seam unloading pressure and enhancing permeability, in order to resolve the problem of insufficient ability of flexible cutting tools breaking coal at the present period, improve the performance of ...
Jianping WEI   +7 more
doaj   +1 more source

The Expression of Neuropeptides in Pulpitis: A Systematic Review and Meta‐Analysis

open access: yesInternational Endodontic Journal, EarlyView.
ABSTRACT Background Neuropeptides play key roles in the inflammatory, nociceptive and reparative processes of the dental pulp. Their upregulation has been frequently observed in inflamed pulps, suggesting potential diagnostic value supporting a role for neurogenic inflammation in symptomatic irreversible pulpitis.
N. Watson   +3 more
wiley   +1 more source

Diffusion ability of endotoxin through dentinal tubules Avaliação da difusão de endotoxinas através dos túbulos dentinários

open access: yesBrazilian Oral Research, 2005
The aim of this study was to evaluate the ability of endotoxin to diffuse through dentinal tubules towards the cement and to observe the period of time needed for it to reach the external root surface.
Luciane Dias de Oliveira   +4 more
doaj   +1 more source

Site‐Resolved Gingival Microcirculation and Colour Features in Health and Early Inflammation

open access: yesJournal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To characterise site‐level gingival microcirculation in health and early inflammation without clinical attachment loss (CAL), and to evaluate its relationship with probing‐derived clinical parameters and scan‐derived gingival colour metrics.
Mengning Bi   +7 more
wiley   +1 more source

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