Results 71 to 80 of about 2,855,255 (284)

Tooth spray with active ingredients casein phosphopeptide – amorphous calcium phosphate (CPP – ACP) and ethanolic extract propolis (EEP) to inhibit tooth demineralization

open access: yesCommunications in Science and Technology, 2016
Dental caries is a disease caused by the microbial infection that produces localized damage to the tissue classification. The process begins by demineralization in hard tissue followed by damage to the organic material.
Muhamad Sahlan , Lucia Purwanti
doaj   +1 more source

Principles of Tooth Preparation - Review Article

open access: yesIndian Journal of Forensic Medicine & Toxicology, 2020
Adequate tooth preparation is essential for the fit of fixed prosthodontics. Insufficient tooth preparationappears to be responsible for premature failures due to biological aspects, such as caries and endodonticor periodontal disease complications.
G. Ramesh, Sanjna Nayar, S. Chandrakala
semanticscholar   +1 more source

From Chatbots to Co‐Scientists: The Impact of Knowledge‐Generating AI (AI 4.0) on Healthcare and Research

open access: yesAdvanced Science, EarlyView.
This perspective contrasts the historical, linear progression of early AI with the dynamic, iterative nature of AI 4.0; and it describes the real‐world medical applications and the necessary evolution of laboratory infrastructure brought about by AI 4.0.
Weida Liu, Gary Peltz
wiley   +1 more source

TRAF6 Lactylation in Glycolytic Macrophages Drives NF‐κB Signaling and M1 Polarization During Orthodontic Tooth Movement

open access: yesAdvanced Science, EarlyView.
Schematic diagram showing compressive stress triggers glycolytic reprogramming and lactate accumulation in macrophages. Lactate mediates TRAF6 lactylation at K171/K180 dual sites, which enhances its K63‐linked ubiquitination to activate the NF‑κB pathway and promote M1 polarization. This cascade drives orthodontic tooth movement (OTM) and alveolar bone
Xinyi He   +9 more
wiley   +1 more source

WDR72 Promotes Neuroblastoma Stemness and Progression by Sequestering TRIM31‐Mediated Degradation of CBX8

open access: yesAdvanced Science, EarlyView.
This study unveiled that METTL14 mediates m6A modification of WDR72 mRNA to stabilize and enhance WDR72 expression, which disrupts TRIM31‐mediated ubiquitination of CBX8 protein and retards its degradation, finally the elevated CBX8 contributes to tumor stemness.
Huijuan Zeng   +13 more
wiley   +1 more source

Targeting the KCNC3‐Dependent Anterior Insular‐Lateral Orbitofrontal Cortex Glutamatergic Circuit Attenuates Post‐Traumatic Anxiety

open access: yesAdvanced Science, EarlyView.
Frontal lobe traumatic brain injury is associated with hyperactivity of an insular–orbitofrontal circuit in both patients and mice. By combination of integrating functional imaging, cell‐type–specific circuit manipulation, single‐cell transcriptomics, and whole‐cell recordings, this work identifies the downregulation of the potassium channel KCNC3 in ...
Meng‐Ge Li   +10 more
wiley   +1 more source

ATL2 Recruits TRAK1 to Promote Mitochondrial Transport at ER–Mitochondria Contact Sites

open access: yesAdvanced Science, EarlyView.
ABSTRACT Mitochondrial transport and distribution are crucial for cellular homeostasis, yet whether and how they are regulated by endoplasmic reticulum (ER)–mitochondria contact sites remains unclear. Here, we demonstrate that the ER protein atlastin‐2 (ATL2) orchestrates mitochondrial transport and distribution by promoting assembly of the transport ...
Yiru Cheng   +9 more
wiley   +1 more source

Frezlerle Ve Sonik Uçlarla Basamaklı Kole Preparasyonu Yapılmış Dişlerin Yüzey Pürüzlülüğünün Karşılaştırmalı Olarak Araştırılması

open access: yesSelcuk Dental Journal, 2020
Amaç: Bu in vitro çalışmanın amacı, sadece döner aletlerde kullanılan normal gren boyutlu elmas frezlerle prepare edilen dişlerin yüzey pürüzlülüğü ile döner aletlerde kullanılan normal gren boyutlu elmas frezler + özel ultra sonik uçlar kullanılarak ...
Ece Tamaç   +2 more
doaj   +1 more source

Protease‐Triggered Chromogenic Release From Peptide‐Modified Calcium Carbonate Microspheres Enables Colorimetric Detection of Porphyromonas gingivalis Activity

open access: yesAdvanced Science, EarlyView.
We report a chromogenic release‐based assay system with protease‐cleavage peptide‐modified calcium carbonate microspheres for colorimetric detection of Porphyromonas (P.) gingivalis activity. In response to Arg‐specific gingipain secreted by P. gingivalis, the supernatant becomes colored, enabling colorimetric analysis and providing the monitoring of ...
Yuki Hiruta   +9 more
wiley   +1 more source

Effect of cavity preparation design and ceramic type on the stress distribution, strain and fracture resistance of CAD/CAM onlays in molars

open access: yesJournal of Applied Oral Science, 2018
Objective This study aimed to evaluate the effect of the cavity preparation and ceramic type on the stress distribution, tooth strain, fracture resistance and fracture mode of human molar teeth restored with onlays.
Ana Luíza Serralha de Velloso VIANNA   +5 more
doaj   +1 more source

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