Results 221 to 230 of about 3,217,305 (276)

Factors Associated With Patient‐Reported Outcomes More Than 5 Years After Dental Implant Therapy: A Cross‐Sectional Study

open access: yesClinical Oral Implants Research, EarlyView.
ABSTRACT Objectives To evaluate patient‐reported outcome (PROs) and their associated factors in patients treated with dental implants more than 5 years earlier. Materials and Methods In this cross‐sectional study, patients with implants (> 5 years) completed a self‐administered questionnaire assessing functional, aesthetic, psychosocial and economic ...
Simone Sbalchiero   +3 more
wiley   +1 more source

Chromatin Remodeller BRD9 Orchestrates Odontoblastic Differentiation via Coordinating RUNX2‐KLF4

open access: yesCell Proliferation, EarlyView.
During odontoblast lineage commitment, the chromatin remodeller BRD9 acts as a critical epigenetic coordinator, orchestrating the chromatin landscape to facilitate synergistic binding of key transcription factors RUNX2 and KLF4 to target loci for odontogenesis.
Wenrui Zeng   +8 more
wiley   +1 more source

Magnesium Enhances Immune Clearance of P. gingivalis in Macrophages by Suppressing MCU‐Mediated Mitochondrial Calcium Overload

open access: yesCell Proliferation, EarlyView.
Magnesium restores macrophage clearance of P. gingivalis by inhibiting MCU‐mediated calcium overload. P. gingivalis is mainly phagocytosed by macrophages but escapes intracellular clearance via MCU‐mediated mitochondrial and cytosolic Ca2+ overload in periodontitis. The persistent P.
Dao‐Kun Deng   +11 more
wiley   +1 more source

AFF4 Loss Compromises Osteogenesis of Orofacial Mesenchymal Stem Cells During Alveolar Bone Repair via AMPK‐Mediated Mitophagy

open access: yesCell Proliferation, EarlyView.
Compromised alveolar socket healing following tooth extraction upon Aff4 knockout is caused by suppressed osteogenic capacity of orofacial mesenchymal stem cells, which results from defective AMPK‐mediated mitophagy. ABSTRACT Repair of maxillofacial bone defects presents significant clinical challenges.
Li Zhu   +7 more
wiley   +1 more source

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