Results 51 to 60 of about 10,390 (284)

Electroacupuncture Improves the Learning and Memory by Modulating Hippocampal Glucose Metabolism through IGF1/IGF1R Signaling in Alzheimer's Disease

Advanced Science, EarlyView.
Electroacupuncture (EA) ameliorates learning and memory function in 5×FAD mice by regulating the brain glucose metabolic network. This neuroprotective effect is closely related to enhancing neuronal energy utilization via the IGF1/IGF1R signaling pathway.
Shengxiang Liang, Qingqing Zhang, Xiuxiu Wang, Lixin Peng, Xinru Ji, Jiawei Wang, Yusi Zhang, Jiayang Huang, Junchao Yang, Shiqi Zhan, Yiping Xiao, Weilin Liu, Lidian Chen   +12 more
wiley   +1 more source

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

Advanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang, Zhongwei Yang, Yunfan Zhang, Longwei Wang, Xiaoyu Zhang, Jiahui Mao, Yizhi Dai, Yifan Yuan, Mingge Wang, Xin Yang, Xin Yu, Jing Liu, Chunying Chen   +12 more
wiley   +1 more source

Influence of Tooth Spacing Error on Gears With and Without Profile Modifications [PDF]

Volume 6: 8th International Power Transmission and Gearing Conference, 2000
Abstract A computer simulation was conducted to investigate the effectiveness of profile modification for reducing dynamic loads in gears with different tooth spacing errors. The simulation examined varying amplitudes of spacing error and differences in the span of teeth over which the error occurs.
Giri Padmasolala, Hsiang H. Lin, Fred B. Oswald   +2 more
openaire   +1 more source

Design Technique Research of Fine-Forged Spur Bevel Gear Tooth Profile Modification

, 2010
Gear tooth profile modification can be featured to improve working stability of gear equipments, abate noise and vibration, enhance loading ability and prolong usage life of the gears.
Huan Yong Cui, Xi Jie Tian, Dong Liang Wang   +2 more
core   +1 more source

Aptamer‐Directed Porous DNA Nanocomposite Hydrogel for Active Pulp Preservation: Immunomodulation, Stem Cell Recruitment and Reparative Dentinogenesis

Advanced Science, EarlyView.
This study presents an injectable DNA‐based porous hydrogel integrating catechol motifs and targeting aptamers for pulpitis management. Upon in situ crosslinking, the scaffold actively recruits endogenous dental pulp stem cells, restores redox homeostasis, and modulates immune responses.
Luhui Cai, Huan Yu, Zihan Ni, Kan Chen, I‐Chen Tsai, Zeyu Bao, Shuo Sun, Weichang Li, Yunhua Chen, Qiong Xu   +9 more
wiley   +1 more source

Tooth surface mismatch modification method of cycloidal bevel gear based on conjugate tooth surface modification

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2020
In order to obtain locally conjugated tooth surface contact, a tooth surface mismatch modification method is proposed based on the fully conjugated characteristics of cycloidal bevel gear.
Jing DENG, Shaowu NIE, Xiaozhong DENG, Chuang JIANG   +3 more
doaj   +1 more source

Beyond Potency: Emerging Determinants and Optimization Strategies Enhancing Therapeutic Efficacy of Adult Stem Cells

Advanced Science, EarlyView.
Adult stem cell therapy requires more than high in vitro potency. This review proposes a systems framework in which cell‐intrinsic programs, instructive microenvironmental cues, and pre‐/post‐delivery engineering are co‐designed under standardized translational rules.
Soo‐Rim Kim, Yun Jae Jung, Hwa‐Yong Lee   +2 more
wiley   +1 more source

Finite Element Analysis for Tooth Profile Modification of Gear-Box of Tracklayer

, 2010
The quasi-static contact finite element analysis of meshing gear of gear-box is computed by using MSC.Marc software, then transmission error and surface contact stress of meshing gear are computed in different tooth profile modification methods.
Hui Yong Deng, Hai Ping Liu, Ji Sheng Ma, Yan Wang   +3 more
core   +1 more source

Light‐Activated Ruthenium Nanoclusters Reprogram the Metabolic‐Quorum Sensing Axis for Precision Periodontitis Therapy

Advanced Science, EarlyView.
Under 660 nm visible light, Ru NCs efficiently photocatalyze nitrate‐to‐ammonium conversion and modulate oral nitrogen metabolism. They precisely perturb Veillonella parvula, block its key support to Porphyromonas gingivalis, and exert an “inhibiting without killing” antivirulence effect.
Jing Zhou, Xiaolin Sun, Chengyu Liu, Yujia Shi, Meiqi Li, Meng Bo, Jingjie Zhai, Chunyan Li, Zhennan Wu, Xue Bai, Lin Wang   +10 more
wiley   +1 more source

Multi-objective Orthogonal Test Simulation and Modification Parameter Design based on Ease-off Topology

Jixie chuandong, 2022
To improve the comprehensive dynamic meshing performance of a certain gear product， a design method for controlling the polynomial coefficients of the topological modification of the tooth surface is proposed.
Jiaqi Li, Congcong Song, Bingyang Wei
doaj