Tooth root resorption: A review. [PDF]
Tooth root resorption is multifactorial, leading to progressive destruction and eventual loss of tooth root dentin and cement. There are internal and external types of root resorption, each having its variety.
Heboyan A +7 more
europepmc +4 more sources
The Role of Wnt Signaling in Postnatal Tooth Root Development [PDF]
Appropriate tooth root formation and tooth eruption are critical for achieving and maintaining good oral health and quality of life. Tooth eruption is the process through which teeth emerge from their intraosseous position to their functional position in
Nicha Tokavanich +5 more
doaj +3 more sources
Spatiotemporal cellular dynamics and molecular regulation of tooth root ontogeny. [PDF]
Tooth root development involves intricate spatiotemporal cellular dynamics and molecular regulation. The initiation of Hertwig’s epithelial root sheath (HERS) induces odontoblast differentiation and the subsequent radicular dentin deposition.
Rao P, Jing J, Fan Y, Zhou C.
europepmc +2 more sources
Mechanisms of Osteoclastogenesis in Orthodontic Tooth Movement and Orthodontically Induced Tooth Root Resorption. [PDF]
Orthodontic tooth movement (OTM) is achieved by the simultaneous activation of bone resorption by osteoclasts and bone formation by osteoblasts. When orthodontic forces are applied, osteoclast-mediated bone resorption occurs in the alveolar bone on the ...
Nakai Y, Praneetpong N, Ono W, Ono N.
europepmc +2 more sources
Self-Assembly of Tooth Root Organoid from Postnatal Human Dental Stem Cells. [PDF]
Challenges remain in simultaneously regenerating the multiple diverse tissues of the tooth root in a spatially organized manner. Previously, our research group has established that scaffold-free tissue engineering approaches enable dental pulp stem ...
Calabrese TC +5 more
europepmc +2 more sources
Current Understanding of the Regulatory Mechanism of Tooth Root Development and Future Perspectives [PDF]
Background The purpose of this review article is to understand tooth root development and its regulation through evolution and epigenetics as well as future implications involving root regeneration and tissue engineering.Types of Studies Reviewed We ...
Natalie Black, Yang Chai
doaj +2 more sources
The formation of the tooth crown implies dentin and pulp construction (including mantle dentin, odontoblasts, Höhl cells, and vascular, axons and pulp cells).
M. Goldberg
semanticscholar +2 more sources
USP34 regulates tooth root morphogenesis by stabilizing NFIC. [PDF]
Tooth root morphogenesis involves two biological processes, root elongation and dentinogenesis, which are guaranteed by downgrowth of Hertwig’s epithelial root sheath (HERS) and normal odontoblast differentiation.
Jiang S +5 more
europepmc +2 more sources
Cell dynamics in Hertwig's epithelial root sheath are regulated by β-catenin activity during tooth root development. [PDF]
β‐catenin, a key mediator of Wnt signaling, plays multiple roles in tooth development. However, the role of β‐catenin in Hertwig's epithelial root sheath (HERS) during root formation remains unclear.
Yang S +6 more
europepmc +2 more sources
Runx2 Regulates Mouse Tooth Root Development Via Activation of WNT Inhibitor NOTUM. [PDF]
Progenitor cells are crucial in controlling organ morphogenesis. Tooth development is a well‐established model for investigating the molecular and cellular mechanisms that regulate organogenesis.
Wen Q +8 more
europepmc +2 more sources

