Wnt-directed CXCL12-expressing apical papilla progenitor cells drive tooth root formation [PDF]
Nature CommunicationsThe tooth root is a critical component of the tooth anchored to surrounding alveolar bones. Tooth root formation is driven by cells in the apical papilla (AP) that generate new dentin-forming odontoblasts at the root-forming front. Mesenchymal stem cells
Mizuki Nagata +16 more
doaj +2 more sources
Bmp9 modulates cell proliferation and intercellular junctions in HERS during tooth root development [PDF]
Genes and DiseasesTooth formation is a highly orchestrated process that precisely regulates the size and shape of the tooth. During typical tooth development, Hertwig's epithelial root sheath (HERS) interacts with mesenchymal cells to direct the elongation of the tooth ...
Chang Liu +13 more
doaj +2 more sources
Cell dynamics in Hertwig's epithelial root sheath are regulated by β-catenin activity during tooth root development. [PDF]
J Cell Physiol, 2021 β‐catenin, a key mediator of Wnt signaling, plays multiple roles in tooth development. However, the role of β‐catenin in Hertwig's epithelial root sheath (HERS) during root formation remains unclear.
Yang S +6 more
europepmc +2 more sources
Runx2 Regulates Mouse Tooth Root Development Via Activation of WNT Inhibitor NOTUM. [PDF]
J Bone Miner Res, 2020 Progenitor cells are crucial in controlling organ morphogenesis. Tooth development is a well‐established model for investigating the molecular and cellular mechanisms that regulate organogenesis.
Wen Q +8 more
europepmc +2 more sources
Simulating coupling behavior of spur gear meshing and fatigue crack propagation in tooth root
International Journal of Fatigue, 2020 Fatigue and fracture behavior at tooth root during gear meshing are critical to the gear transmission performance. This paper presents a study of the coupling behavior of spur gear meshing and tooth root crack propagation.
Xi Wang +3 more
semanticscholar +3 more sources
Development, 2021 The control of size and shape is an important part of regulatory process during organogenesis. Tooth formation is a highly complex process that fine-tunes the size and shape of the tooth, which are crucial for its physiological functions.
Ma Y +9 more
europepmc +2 more sources
Some historical musings on tooth/root resorption. [PDF]
J Istanb Univ Fac Dent, 2017 Contemporarily, the ravages of tooth resorption are seen daily around the world. While some teeth can be retained many are lost to this process. Although many types of resorptive processes have been identified, the etiological factors involved in this malady are not often clear and both speculation as to it source and clinical management have received ...
Gutmann JL.
europepmc +5 more sources
BMP signaling in the development and regeneration of tooth roots: from mechanisms to applications
Frontiers in Cell and Developmental Biology, 2023 Short root anomaly (SRA), along with caries, periodontitis, and trauma, can cause tooth loss, affecting the physical and mental health of patients.
Cangwei Liu +7 more
doaj +1 more source
Dynamic Simulation of Cracked Spiral Bevel Gear Pair Considering Assembly Errors
Machines, 2022 The tooth root crack fault is a common fault type of the spiral bevel gear pair (SBGP). Affected by the strong bearing capacity, the early crack fault of the SBGP cannot be found in time.
Hongzheng Han +5 more
doaj +1 more source
Tooth Root Bending Fatigue Performance of Shot Peening TM210A Steel Spur Gear
Advances in Materials Science and Engineering, 2022 Tooth root bending fatigue performance is the primary consideration in gear design. To investigate the difference between the tooth root fatigue performances of shot peened and base material, TM210A steel gears and double-tooth pulsating bending fatigue ...
H. J. Xu +3 more
doaj +1 more source