Results 81 to 90 of about 1,575,820 (393)

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

open access: yesAdvanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang   +16 more
wiley   +1 more source

Fracture Resistance of Compromised Endodontically Treated Teeth Restored with Bonded Post and Cores: An in Vitro Study [PDF]

open access: yes, 2015
Statement of problem: It is unclear which post and core system performs best when bonded to severely compromised endodontically treated teeth. Purpose: The purpose of this study was to investigate the fracture resistance and mode of failure of severely ...
Kontogiorgos, Elias D.   +2 more
core   +2 more sources

Nutritional c‐Fos Induction Rewires Hepatic Metabolism and Can Promote Obesity‐Associated Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
It is shown that hepatic c‐Fos responds to feeding, altering de novo lipogenesis, glycolysis, and a wide range of steatosis‐associated metabolic signaling pathways. Obesogenic diets cause hepatic c‐Fos overexpression, insulin resistance, and the induction of metabolic reprogramming‐related genes.
Ao Li   +8 more
wiley   +1 more source

Geometrically Encoded Positioning of Introns, Intergenic Segments, and Exons in the Human Genome

open access: yesAdvanced Science, EarlyView.
This study introduces a new hypothesis: exons, introns, and intergenic segments are non‐random projections of the functional layers of 3D structure of chromatin packing domains. Evidence is presented that this “geometric code” may encode volumetric structure, reconciling epigenetic patterns, correlates with oncogenic mutations, acting as a potential ...
Luay M. Almassalha   +11 more
wiley   +1 more source

Hybodont sharks of the English Bathonian and Callovian (Middle Jurassic). [PDF]

open access: yes, 2008
Recent bulk sampling and study of museum collections has revealed a high diversity of hybodont sharks from the English Bathonian, with 15 species being recognised.
AGASSIZ   +76 more
core   +1 more source

Effect of Low Intensity Pulsed Ultrasound (LIPUS) on Tooth Movement and Root Resorption: A Prospective Multi-Center Randomized Controlled Trial

open access: yesJournal of Clinical Medicine, 2020
The aim of this study was to evaluate the possible effect of low intensity pulsed ultrasound (LIPUS) on tooth movement and root resorption in orthodontic patients. Twenty-one patients were included in a split-mouth study design (group 1).
T. El-Bialy   +7 more
semanticscholar   +1 more source

Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis

open access: yesAdvanced Science, EarlyView.
Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and
Hoang Thai Ha   +12 more
wiley   +1 more source

Radiation-induced root surface caries restored with glass-ionomer cement placed in conventional and ART cavity preparations: Results at two years [PDF]

open access: yes, 2005
The document attached has been archived with permission from the Australian Dental Association (8th Jan 2008). An external link to the publisher’s copy is included.Background: There are no published studies comparing the clinical performances of more ...
American Dental Association.   +13 more
core   +2 more sources

Engineering Dimensional Configuration of Single‐Atom S‐Cu‐S Sites as Reversible Electron Station for Enhanced Peroxidase‐Mimicking

open access: yesAdvanced Science, EarlyView.
L‐cysteine triggers auto‐assembly of POD‐like 3D biomimetic S‐Cu‐S single‐atom nanozymes on MoS2 (MoCC). MoCC shows 16.3‐fold higher catalytic velocity and 17.9‐fold greater affinity than HRP, enabling efficient •OH generation via enhanced electron inversion and transfer.
Wenjie Ma   +12 more
wiley   +1 more source

渐开线齿轮齿根过渡曲线最佳线型实现方法

open access: yesJixie chuandong, 2013
Based on finite element optimization analysis principle and using of characteristics of NURBS spline curve,through the shape optimization of standard involute gear tooth root part operated in Pro/E and ANSYS workbench software,a new realization method of
董新华, 马勇, 柳强
doaj  

Home - About - Disclaimer - Privacy