Results 61 to 70 of about 48,631 (290)

Arginine Methylation Antagonizes TEAD3‐Mediated Repression to Promote Osteogenic Differentiation by Disrupting RUNX2‐Sequestrating Condensates

open access: yesAdvanced Science, EarlyView.
In the unmethylated state, TEAD forms stable, repressive condensates that sequester the osteogenic master regulator RUNX2. Arginine methylation of TEAD at R55 acts as a molecular brake, dissolving these condensates to release RUNX2 and activate the osteogenic program.
Lei Cao   +6 more
wiley   +1 more source

Identification of a Force‐Induced Sox9+Acan+ Transitional Subpopulation Linked to FGF2–FGFR2–ERK Signaling in Orthodontic Bone Remodeling

open access: yesAdvanced Science, EarlyView.
Mechanical loading induces a previously unrecognized Sox9+Acan+ transitional mesenchymal cell population in the periodontal ligament that promotes osteoclastogenesis via the FGF2–FGFR2–ERK axis. Targeting this mechanoresponsive stromal population using a localized GelMA@siRNA delivery strategy attenuates pathological osteoclast overactivation and root ...
Miao Tan   +9 more
wiley   +1 more source

VITAL TOOTH BLEACHING: SENSITIVITY AND PULPAL CONSIDERATIONS

open access: yesThe Journal of the American Dental Association, 1997
For some patients, sensitivity and discomfort follow vital tooth bleaching. Clinical observations, however, suggest these are reversible episodes with no irreversible long-term effects. Using milder peroxide formulations or gels diminishes postoperative discomfort.
openaire   +2 more sources

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

open access: yesAdvanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li   +7 more
wiley   +1 more source

Cascade Therapy of Periodontitis via Sequential Release of Ribosome‐Targeting Antimicrobial Peptide and Irisin From a Multifunctional MOF‐Based System

open access: yesAdvanced Science, EarlyView.
This study presents a novel strategy for periodontitis treatment by co‐delivering a membrane‐ and ribosome‐targeting antimicrobial peptide GF and Irisin through a pH‐responsive metal‐organic framework. The system enables sequential release, providing rapid antibacterial action, anti‐inflammatory and antioxidative effects, as well as promoting bone ...
Yan Chen   +10 more
wiley   +1 more source

Comparison of In-office Bleaching Agent Application Times on Tooth Sensitivity and Color Change: A Systematic Review and Meta-analysis [PDF]

open access: yesInternational Journal of Prosthodontics and Restorative Dentistry
Purpose: To compare the effect of in-office bleaching agent application times on tooth sensitivity and degree of color change. Materials and methods: PubMed, Web of Science, EBSCO, Scopus, Cochrane Library, DOAJ, LILAC, gray literature, and manual search.
Yasmeen M Azeem   +4 more
doaj   +1 more source

Interface Engineering Strategies for Realizing Anode‐Free Sodium Batteries: A Review

open access: yesAdvanced Energy Materials, EarlyView.
This review examines anode‐free sodium batteries as a promising solution for advancing sodium‐based energy storage. It focuses on the role of interface engineering in addressing challenges such as sodium deposition, interface stability, and dendrite growth.
Yulian Dong   +6 more
wiley   +1 more source

Sensitivity analysis and compensation for tooth surface deviation of spiral bevel gear machine tool

open access: yesScientific Reports
To analyze the quantitative mapping relationship between the geometric errors of the five-axis CNC machine tool and the tooth surface deviation of spiral bevel gears, and identify the key geometric errors that affect the machining deviation of the spiral
Jianjun Yang   +5 more
doaj   +1 more source

Effect of low-level laser therapy in tooth bleaching sensitivity:

open access: yesRevista da Faculdade de Odontologia de Porto Alegre
Aim: Tooth sensitivity is the principal side effect as a clinical consequence resulting from tooth bleaching. Therefore, several strategies have been proposed to control this adverse effect. The present study aimed to investigate the effect of low-level
Suéllen Gomes Siqueira   +3 more
doaj   +1 more source

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