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The role of IFT140 in early bone healing of tooth extraction sockets
Oral Diseases, 2021AbstractObjectivesPrimary cilium is a key organelle of regulating bone development and maintenance. The aim of this study is to investigate whether ciliary intraflagellar transporter protein 140 (IFT140) plays a positive role in extraction socket healing by promoting bone formation.Materials and MethodsA left maxillary first molar extraction model was ...
Shuang Zhou+7 more
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Healing of tooth extraction sockets in experimental diabetes mellitus
Journal of Oral and Maxillofacial Surgery, 1996This study was undertaken to examine the healing of molar tooth extraction sockets in the streptozotocin-treated, diabetic rat.Insulin-dependent diabetes mellitus was induced in a group of mature Sprague-Dawley rats by injecting streptozotocin. Control animals were injected with citrate buffer only.
H Garland, Philip Sloan, Hugh Devlin
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Molecular events on tooth socket healing in diabetic rabbits
British Journal of Oral and Maxillofacial Surgery, 2013Healing of extraction sockets involves complex cellular events such as repair and regeneration of tissue. These events are precisely controlled and regulated by specific signalling molecules such as transforming growth factor beta (TGF-β), vascular endothelial growth factor (VEGF), bone morphogenetic protein (BMP), and insulin-like growth factor (IGF),
Mohamed Abdul-Hameed Mohamed+3 more
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On the part played by the socket in tooth support
Archives of Oral Biology, 1965Abstract Transducers of movement were used to detect the direction and amount of displacement of the alveolar margins of fifteen teeth in two adult monkeys. Controlled horizontal and intrusive thrusts were applied manually. Bone displacement started in response to forces appreciably less than 100 g and occurred in a linear manner with forces up to 1 ...
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Role of p53 deficiency in socket healing after tooth extractions
Journal of Molecular Histology, 2020p53 is known to advance the cell arrest and cell senescence in human tumors. In this study, we displayed that osteogenic ability of p53-knockout (p53-/-) mice was significantly increased in the tooth extraction socket compared with wild-type (WT) counterparts.
Xiaohan Yang+5 more
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Root development of rat tooth germs implanted in the tooth socket and in the subcutaneous tissue
Oral Diseases, 2008Objective: This study was designed to investigate root development of a rat tooth germ implanted in a tooth socket or in a subcutaneous region.Materials and methods: Tooth germs of the upper left first molars in 2‐week‐old rats were extracted and implanted in the original tooth socket or in the subcutaneous region of the back.
Y. Ina+5 more
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Abnormal macrophage polarization impedes the healing of diabetes-associated tooth sockets
Bone, 2021Patients with poorly controlled type 2 diabetes mellitus (T2DM) often experience delayed tooth extraction socket (TES) healing. Delayed healing is often associated with an aberrant inflammatory response orchestrated by either M1 pro-inflammatory or M2 anti-inflammatory macrophages.
Yifei Du+8 more
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[The effect of osteogenic inducer on healing of tooth extraction sockets].
Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology, 2012To study the effect of osteogenic inducer (dexamethasone, beta-sodium glycerophosphate and Vitamin C) carried by gelatin sponge on healing and remodeling of tooth extraction sockets.Fifty rabbits were selected. After extracting the first premolars of bilateral maxillary, the right side tooth extraction sockets were filled with gelatin sponge containing
Chuncheng Shan+3 more
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Sodium hyaluronate accelerates the healing process in tooth sockets of rats
Archives of Oral Biology, 2008In this study we evaluated the effects of sodium hyaluronate (HY) in the healing process of tooth sockets of rats.Immediately after the extraction of the upper first molars of male Holtzman rats, right sockets were treated with 1% HY gel (approximately 0.1 ml), while left sockets were used as control (blood clot).
Miguel F. Lima+6 more
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Effect of CBX7 deficiency on the socket healing after tooth extractions
Journal of Bone and Mineral Metabolism, 2018CBX7 is shown to down-regulate the expression of osteopontin (OPN) that is associated with osteoblast function. Here, we studied the role of CBX7 in the wound healing of tooth extraction socket in which osteoblast activity is critical via comparison between CBX7-knockout (CBX7-/-) mice and their wild-type (WT) counterparts of 6 weeks old with maxillary
Zhixuan Zhou+4 more
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