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The role of IFT140 in early bone healing of tooth extraction sockets

Oral Diseases, 2021
AbstractObjectivesPrimary cilium is a key organelle of regulating bone development and maintenance. The aim of this study is to investigate whether ciliary intraflagellar transporter protein 140 (IFT140) plays a positive role in extraction socket healing by promoting bone formation.Materials and MethodsA left maxillary first molar extraction model was ...
Shuang Zhou   +7 more
openaire   +2 more sources

Healing of tooth extraction sockets in experimental diabetes mellitus

Journal of Oral and Maxillofacial Surgery, 1996
This study was undertaken to examine the healing of molar tooth extraction sockets in the streptozotocin-treated, diabetic rat.Insulin-dependent diabetes mellitus was induced in a group of mature Sprague-Dawley rats by injecting streptozotocin. Control animals were injected with citrate buffer only.
H Garland, Philip Sloan, Hugh Devlin
openaire   +3 more sources

Molecular events on tooth socket healing in diabetic rabbits

British Journal of Oral and Maxillofacial Surgery, 2013
Healing of extraction sockets involves complex cellular events such as repair and regeneration of tissue. These events are precisely controlled and regulated by specific signalling molecules such as transforming growth factor beta (TGF-β), vascular endothelial growth factor (VEGF), bone morphogenetic protein (BMP), and insulin-like growth factor (IGF),
Mohamed Abdul-Hameed Mohamed   +3 more
openaire   +3 more sources

On the part played by the socket in tooth support

Archives of Oral Biology, 1965
Abstract Transducers of movement were used to detect the direction and amount of displacement of the alveolar margins of fifteen teeth in two adult monkeys. Controlled horizontal and intrusive thrusts were applied manually. Bone displacement started in response to forces appreciably less than 100 g and occurred in a linear manner with forces up to 1 ...
openaire   +3 more sources

Role of p53 deficiency in socket healing after tooth extractions

Journal of Molecular Histology, 2020
p53 is known to advance the cell arrest and cell senescence in human tumors. In this study, we displayed that osteogenic ability of p53-knockout (p53-/-) mice was significantly increased in the tooth extraction socket compared with wild-type (WT) counterparts.
Xiaohan Yang   +5 more
openaire   +3 more sources

Root development of rat tooth germs implanted in the tooth socket and in the subcutaneous tissue

Oral Diseases, 2008
Objective:  This study was designed to investigate root development of a rat tooth germ implanted in a tooth socket or in a subcutaneous region.Materials and methods:  Tooth germs of the upper left first molars in 2‐week‐old rats were extracted and implanted in the original tooth socket or in the subcutaneous region of the back.
Y. Ina   +5 more
openaire   +3 more sources

Abnormal macrophage polarization impedes the healing of diabetes-associated tooth sockets

Bone, 2021
Patients with poorly controlled type 2 diabetes mellitus (T2DM) often experience delayed tooth extraction socket (TES) healing. Delayed healing is often associated with an aberrant inflammatory response orchestrated by either M1 pro-inflammatory or M2 anti-inflammatory macrophages.
Yifei Du   +8 more
openaire   +3 more sources

[The effect of osteogenic inducer on healing of tooth extraction sockets].

Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology, 2012
To study the effect of osteogenic inducer (dexamethasone, beta-sodium glycerophosphate and Vitamin C) carried by gelatin sponge on healing and remodeling of tooth extraction sockets.Fifty rabbits were selected. After extracting the first premolars of bilateral maxillary, the right side tooth extraction sockets were filled with gelatin sponge containing
Chuncheng Shan   +3 more
openaire   +3 more sources

Sodium hyaluronate accelerates the healing process in tooth sockets of rats

Archives of Oral Biology, 2008
In this study we evaluated the effects of sodium hyaluronate (HY) in the healing process of tooth sockets of rats.Immediately after the extraction of the upper first molars of male Holtzman rats, right sockets were treated with 1% HY gel (approximately 0.1 ml), while left sockets were used as control (blood clot).
Miguel F. Lima   +6 more
openaire   +3 more sources

Effect of CBX7 deficiency on the socket healing after tooth extractions

Journal of Bone and Mineral Metabolism, 2018
CBX7 is shown to down-regulate the expression of osteopontin (OPN) that is associated with osteoblast function. Here, we studied the role of CBX7 in the wound healing of tooth extraction socket in which osteoblast activity is critical via comparison between CBX7-knockout (CBX7-/-) mice and their wild-type (WT) counterparts of 6 weeks old with maxillary
Zhixuan Zhou   +4 more
openaire   +3 more sources

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