Results 141 to 150 of about 2,282 (237)

Hyperactive KIF5A in Neurodegeneration

Cytoskeleton, EarlyView.
ABSTRACT The highly polarised morphology of neurons and the sheer length of their axons make transport of cargoes throughout the cell a formidable task. Decades of evidence obtained from genetic studies on patients and animal models highlight deficits in axonal transport as a recurrent cause, or early contributing factor, in a plethora of ...
David Villarroel‐Campos, James N. Sleigh   +1 more
wiley   +1 more source

Light and Shadows: Insights from Large-Scale Visual Screens for Arabidopsis Leaf Morphology Mutants. [PDF]

Int J Mol Sci
Juan-Vicente L, Ruiz-Bayón A, Micol JL.
europepmc   +1 more source

Mechanism of “seesaw‐type” rock burst in coal seam mining beneath mountainous areas

Deep Underground Science and Engineering, EarlyView.
This study reveals the mechanism of “seesaw‐type” rock bursts during coal mining beneath mountainous areas. The advancing working face induces nonuniform fracturing of the overburden. The detached mountain mass then undergoes a seesaw‐type rotational movement around a shifting pivot, driving the primary fracture through a characteristic “open‐close ...
Chao Zhou, Xueqiu He, Zhenlei Li, Ping Wang, Dazhao Song, Fuxing Jiang, Shan Yin, Anliang Lü, Menghan Wei, Taoping Zhong   +9 more
wiley   +1 more source

Morphology and Glycan Composition of the Mandibular Glands in the White-Eared Opossum (Didelphis albiventris). [PDF]

J Morphol
Schimming BC, Farha AH, Sasahara THC, Abdala FCM, Cianciotta A, Gomes SP, Desantis S.   +6 more
europepmc   +1 more source

Proteomic profiling of Elp1‐deficient trigeminal ganglia reveals disruption of neurotrophic and metabolic pathways in a familial dysautonomia mouse model

Developmental Dynamics, EarlyView.
Abstract Background Elp1, a subunit of the Elongator complex, is essential for tRNA modification and neuronal development. Mutations in ELP1 underlie familial dysautonomia (FD), a disorder marked by sensory and autonomic neuropathy. While loss of Elp1 disrupts trigeminal ganglion formation and survival, the downstream molecular consequences remain ...
Carrie E. Leonard, Lauren Clarissa Tang, Beatrix Ueberheide, Lisa A. Taneyhill   +3 more
wiley   +1 more source

Morphological Investigation of the Roe Deer (Capreolus capreolus) Os Hyoideum and Creating a 3D Model. [PDF]

Vet Med Sci
Sizer SS, Keskin FS, Kurt S, Kanik B, Kabak YB, Onuk B, Kabak M.   +6 more
europepmc   +1 more source

Membrane lipid metabolism as a regulatory frontier in neural crest biology: Roles for sphingolipids, cholesterol, and lipid rafts

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are multipotent, migratory stem‐like cells essential for vertebrate development that contribute broadly to many tissues including the craniofacial skeleton, peripheral nervous system, and pigment‐producing cells. Their development progresses through phases of induction, specification, delamination, migration, and ...
Allison E. Mancini, Mallorie P. Jenne, Michael L. Piacentino   +2 more
wiley   +1 more source

Enterprising a Central Sterile Supplies Department of an Otolaryngology & ENT Hospital. [PDF]

Indian J Otolaryngol Head Neck Surg
Daga SS, Kumar PN.
europepmc   +1 more source

Ullmann‐Type N‐Heteroarylation of Nitrogen Heterocycles Catalyzed by Heterogeneous CuNPs/HKUST‐1

EcoEnergy, EarlyView.
A practical strategy for the direct synthesis of CuNPs/HKUST‐1 heterogeneous catalyst was developed and used for the catalyzing Ullmann‐type N‐arylation of N‐heterocycles with high yields, excellent recyclability, and low copper leaching. ABSTRACT Ullmann‐type C–N coupling is an essential reaction to construct functional nitrogen heterocycles, whereas ...
Shuai Yang, Fangshu Han, Yamin Dong, Liangting Wu, Wenchao Tang, Changyan Guo, Jide Wang, Ablimit Abdukader, Chenjiang Liu, Yonghong Zhang   +9 more
wiley   +1 more source

Description of a collaborative sperm whale birth and shifts in coda vocal styles during key events. [PDF]

Sci Rep
Aluma Y, Baron Z, Barrett R, Baumgartner C, Beguš G, Bhattacharya S, Bronstein MM, Dahan S, Davis O, de Haas S, Defoe J, DelPreto J, Dessi R, Diamant R, Gatesy J, George K, Gero S, Gibbons D, Gibbons D, Gil S, Goldwasser S, Gruber DF, Harve O, Hernandez A, Ishay M, Jadhav N, Kc L, Kenny A, Leitao A, Lucas M, Maalouf A, Malkin P, Mevorach Y, Pagani S, Paradise O, Petri G, Poetto S, Rossi E, Rus D, Salino-Hugg M, Santoro A, Sharma P, Tchernov D, Torralba A, Tønnesen P, Vogt DM, Wood RJ.   +46 more
europepmc   +1 more source