Results 171 to 180 of about 2,282 (237)

Applied surgical anatomical approach to pudendal nerve: Step‐by‐step key neurovascular structures for pelvic nerve surgery

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To define and demonstrate a step‐by‐step surgical anatomical approach to pudendal nerve dissection using female cadavers, focusing on the identification of safe roadmap and key neurovascular structures to optimize pelvic nerve surgery.
Merve Didem Eşkin Tanrıverdi, Ayhan Cömert, Zekiye Gözde Kara, Hasan Onur Topçu, Halil İbrahim Açar   +4 more
wiley   +1 more source

Compound Ecoclimatic Events: The Long-Term Recovery of Conservation-Priority Mammals After an Extreme Ice Storm Event Was Promoted by the Alleviation of Poaching. [PDF]

Glob Chang Biol
Zhou Y, Cui J, Chen W, Wu N, Newman C, Li J, Wang Q, Lei B, Jiang G, Wu J, Buesching CD, Zhao J, Macdonald DW, Stenseth NC.   +13 more
europepmc   +1 more source

N6‐Methyladenosine in Inflammatory Bowel Disease: An Emerging Regulator of Pathogenesis and a Novel Therapeutic Frontier

iMetaMed, EarlyView.
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the intestine associated with an imbalance in intestinal homeostasis. m6A‐modifying enzymes, consisting of m6A writers, erasers and readers, plays a pivotal role in the pathogenesis and progression of IBD by affecting four intestinal barriers, including the intestinal mechanical ...
Jiaxian Guo, Yang Zhang, Xin Wang, Shan Cao, Jun Xu   +4 more
wiley   +1 more source

Evolutionary escalation in an exceptionally preserved Cambrian biota from the Grand Canyon (Arizona, USA). [PDF]

Sci Adv
Mussini G, Hagadorn JW, Miller AE, Karlstrom KE, Evans R, Dehler CM, Bastien S, Butterfield NJ.   +7 more
europepmc   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Evolution of ion channels in cetaceans: a natural experiment in the tree of life. [PDF]

Sci Rep
Uribe C, Nery MF, Zavala K, Mardones GA, Riadi G, Opazo JC.   +5 more
europepmc   +1 more source

Multi‐omics–driven precision medicine

iMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li, Zhe Zhao, Yifan Zhang, Yao Ma, Gaofei Hu, Min Zeng, Zhanqun Yang, Zixuan Zhao, Xin Zhou, Wei Hu, Yuxuan Sun, Meng Su, Jun Li, Matthew Whiteman, Wei Fu, Chao Zhong, Lemin Zheng, Long Chen, Hairong Lv, Rongsheng Zhao, Yi Zhun Zhu   +20 more
wiley   +1 more source

Sensing Underwater: Diversifying Selection, Convergent Evolution and Inactivation in Sensory Receptors' Genes of Aquatic Mammals. [PDF]

J Mol Evol
Lein-Borba AL, Selleghin-Veiga G, Daros B, Magpali L, Nery MF.   +4 more
europepmc   +1 more source

Ordered assembly of Cas12a for better performance of CRISPR/Cas system with application to the diagnosis of dental caries

Interdisciplinary Medicine, EarlyView.
Here, we present a tetrahedral DNA framework (TDF)‐mediated Cas12a ordered assembly strategy. TDFs arrange CRISPR/Cas12a into ordered structures controllably, enhancing catalytic efficiency through localized Cas12a hotspots while maintaining spatial intervals to facilitate substrate diffusion.
Yining Zhao, Panpan Qiao, Yujing Zeng, Murtaza Sayed, Qin Mi, Juan Zhang, Genxi Li   +6 more
wiley   +1 more source

Study on the influence of anchor plate parameters on the bearing characteristics of the new large-diameter multi-plate soil anchor and creep property of anchor. [PDF]

Sci Rep
Wang J, Xia H, Cai H, Hua J.
europepmc   +1 more source